| Basic Information | |
|---|---|
| Species | Cucumis sativus |
| Cazyme ID | Cucsa.165010.1 |
| Family | GT47 |
| Protein Properties | Length: 354 Molecular Weight: 39493.4 Isoelectric Point: 8.4326 |
| Chromosome | Chromosome/Scaffold: 01153 Start: 403769 End: 405019 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 61 | 284 | 4.5e-38 |
| SQAESLFFKSLLNSPYATHDPDQAHLFFIPFSPHISTRSLARLIRTLRTDLPYWNRTLGADHFFLSSSGIGYISDRNVVELKKNAIQVSSFPVSPGKFIP HKDVSLPPVSTLVSTPVSASTVSERMLGFVGYGWVKGLSLVKELIEDPEFLMESEPPRTPSCYGDKLAKSDFCLFEYEGGDVSGIGEALRFGCVPVVISD RWIQDLPLMDVVRWEEMAVFVAGG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 354 Download |
| MASSLITLSL LLSFSLLFTP ITPSPSPSPY LSPIFLKNYN SMSANLRIFT YIPFNPFSFS 60 SQAESLFFKS LLNSPYATHD PDQAHLFFIP FSPHISTRSL ARLIRTLRTD LPYWNRTLGA 120 DHFFLSSSGI GYISDRNVVE LKKNAIQVSS FPVSPGKFIP HKDVSLPPVS TLVSTPVSAS 180 TVSERMLGFV GYGWVKGLSL VKELIEDPEF LMESEPPRTP SCYGDKLAKS DFCLFEYEGG 240 DVSGIGEALR FGCVPVVISD RWIQDLPLMD VVRWEEMAVF VAGGGGIEGV KKVLRRVDGE 300 RLDRMKKLGA AAAQHFVWNS PPQPLDAFNT VAYQLWVRRH AVRYADRREW AQN* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-34 | 42 | 297 | 297 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002282317.1 | 0 | 28 | 351 | 30 | 360 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002307304.1 | 0 | 30 | 344 | 68 | 406 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002311191.1 | 0 | 7 | 351 | 3 | 345 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002316258.1 | 0 | 7 | 351 | 3 | 339 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524235.1 | 0 | 1 | 350 | 1 | 336 | conserved hypothetical protein [Ricinus communis] |
