| Basic Information | |
|---|---|
| Species | Cucumis sativus |
| Cazyme ID | Cucsa.193300.1 |
| Family | GH29 |
| Protein Properties | Length: 442 Molecular Weight: 50020.4 Isoelectric Point: 7.6369 |
| Chromosome | Chromosome/Scaffold: 01335 Start: 269138 End: 271837 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 1 | 288 | 0 |
| MFLHFGPNTFTDSEWGTGAESPAIFNPTALNATQWAATAAAAGISLMILTAKHHDGFCLWPSKYTTHSVSRSPWKNGQGDVVEEFVTAATAHGIDVGLYL SPWDRHDRRYSHDLPYNEYYLAQLQELLKRYGNVKEIWFDGAKGQNAPNMSYYFSDWFAMVKELQSSINIFSDAGPDVRWVGNEKGFAGTSCWSTINRTS LAIGAEGITPYLNKGDPRGRDWVPPECDVSIREGWFWHKTQSPKTLEHLLKIYYNSVGRNCVLLINVPPNSTGLIPQKDAQVLKQFKN | |||
| Full Sequence |
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| Protein Sequence Length: 442 Download |
| MFLHFGPNTF TDSEWGTGAE SPAIFNPTAL NATQWAATAA AAGISLMILT AKHHDGFCLW 60 PSKYTTHSVS RSPWKNGQGD VVEEFVTAAT AHGIDVGLYL SPWDRHDRRY SHDLPYNEYY 120 LAQLQELLKR YGNVKEIWFD GAKGQNAPNM SYYFSDWFAM VKELQSSINI FSDAGPDVRW 180 VGNEKGFAGT SCWSTINRTS LAIGAEGITP YLNKGDPRGR DWVPPECDVS IREGWFWHKT 240 QSPKTLEHLL KIYYNSVGRN CVLLINVPPN STGLIPQKDA QVLKQFKNTI DRIFTTNLAQ 300 NCSIKASSQR GQEFGPQNVI DDDHLWTYWA PKEDVDDHWI EVRSQGNEQL RFNVVRIQEA 360 IGLGQRIGRH EIYLDGKRIV DERESRSIGY KRLYRIKSGV VCGYALKVRF IEFKGVPLIS 420 SLGLHLDPFW NPIRLSSVPT N* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK00945 | PRK00945 | 0.003 | 82 | 164 | 95 | + acetyl-CoA decarbonylase/synthase complex subunit epsilon; Provisional | ||
| pfam00754 | F5_F8_type_C | 0.0001 | 303 | 377 | 80 | + F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. | ||
| smart00812 | Alpha_L_fucos | 1.0e-24 | 47 | 286 | 257 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| pfam01120 | Alpha_L_fucos | 3.0e-26 | 1 | 286 | 321 | + Alpha-L-fucosidase. | ||
| COG3669 | COG3669 | 2.0e-49 | 2 | 291 | 301 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 1 | 432 | 33 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 1 | 432 | 30 | 461 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 1 | 432 | 51 | 482 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 1 | 432 | 52 | 483 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 1 | 433 | 53 | 484 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 2 | 425 | 25 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 2 | 425 | 25 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3ues_B | 0 | 2 | 420 | 34 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 2 | 420 | 34 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 2 | 420 | 36 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX044171 | 295 | 83 | 371 | 0 |
| EY198039 | 319 | 116 | 430 | 0 |
| DR921868 | 306 | 135 | 433 | 0 |
| DT755366 | 266 | 81 | 342 | 0 |
| HE642643 | 265 | 1 | 265 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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