y
Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.235520.1 |
Family | GT47 |
Protein Properties | Length: 665 Molecular Weight: 76564 Isoelectric Point: 9.3019 |
Chromosome | Chromosome/Scaffold: 02012 Start: 40832 End: 44758 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 332 | 615 | 0 |
ERTLKIYVYRDGKKPIFHQPILKGLYASEGWFMKLMEGNKRFVVKDPRKAHLFYMPFSSRMLEYTLYVRNSHNRTNLRQFLKEYAENIAAKYPYWNRTGG ADHFLAGCHDWAPYETRHHMEHCIKALCNADVTVGFKIGRDVSLPETYVRSARNPLRDLGGKPASQRHILAFYAGNMHGYVRPILLKYWKDKNPDMKIFG PMPPGVASKMNYIQHMKSSKYCICPKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEVLDWEAFSVIVAEKDIPNLQDILLSI |
Full Sequence |
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Protein Sequence Length: 665 Download |
MGYLLLPCNL CHIQTRRCLL LVGVVAFTYL IFQSLLLPYG DALRSLLPED AIHKYDHYNI 60 QFGPNSPKLA TVRNPLTVLD LANVSTTPIG KIDKGFQRDN LLNSKGEYVK EEEIPREVDF 120 GSESGNNVDA NGNLESDGTK NRANDSILPV DGETSFGFPL KQQVVKPSDT NTITLENELE 180 DFGQMDLDFG ELEEFKNSSL QKLEDTDMPF NSSTFMLQTS TSTVNTIHSH QLLSNLSSSA 240 SETNSTSIGK RKKMKSELPP KTVTTLEEMN RILFRHRRSS RAMRPRRSSL RDQEIFSAKS 300 LIVQASAVND PELYAPLFRN VSMFKRSYEL MERTLKIYVY RDGKKPIFHQ PILKGLYASE 360 GWFMKLMEGN KRFVVKDPRK AHLFYMPFSS RMLEYTLYVR NSHNRTNLRQ FLKEYAENIA 420 AKYPYWNRTG GADHFLAGCH DWAPYETRHH MEHCIKALCN ADVTVGFKIG RDVSLPETYV 480 RSARNPLRDL GGKPASQRHI LAFYAGNMHG YVRPILLKYW KDKNPDMKIF GPMPPGVASK 540 MNYIQHMKSS KYCICPKGYE VNSPRVVEAI FYECVPVIIS DNFVPPFFEV LDWEAFSVIV 600 AEKDIPNLQD ILLSIPKDRY LEMQLRVRKV QKHFLWHAKP LKYDLFHMTL HSIWYNRVFQ 660 IKLR* 720 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-64 | 331 | 615 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 10 | 660 | 719 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 10 | 662 | 10 | 711 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 175 | 664 | 95 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 258 | 664 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 10 | 664 | 10 | 676 | catalytic, putative [Ricinus communis] |