Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.236080.1 |
Family | GT47 |
Protein Properties | Length: 479 Molecular Weight: 54172.5 Isoelectric Point: 8.7886 |
Chromosome | Chromosome/Scaffold: 02014 Start: 45751 End: 48719 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 54 | 403 | 0 |
SHQSIKVYIADLPRSLNYGLLDQYWAIQSDSRLGSDADRAIRSTQMKKPLQFPPYPENPLIKQYSAEYWILGDLMTPQEQRDGSFAKRVFEAEEADVIFV PFFATMSAEMQLGMAKGAFRKKVGNEDYERQRNVMDFLKSTDAWKKSGGRDHVFVLTDPVAMWHVKAEIAPAVLLVVDFGGWFRLDTKSSNGSSPDMIQH TQVSVLKDVIVPYTHLLPRLHLSANKKRQTLLYFKGAKHRHRGGLVREKLWDLLVNEPDVIMEEGFPNATGKEQSIKGMRSSEFCLHPAGDTPTSCRLFD AIQSLCIPVVVSDNIELPFEDMVDYSEFSVFVAVNDALKPNWLVKHLRTI |
Full Sequence |
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Protein Sequence Length: 479 Download |
MAQKTNSCLC SIPILFLLTL LLTLLFSIFL LFTSSSNPIS SPSSSLFNPN IPPSHQSIKV 60 YIADLPRSLN YGLLDQYWAI QSDSRLGSDA DRAIRSTQMK KPLQFPPYPE NPLIKQYSAE 120 YWILGDLMTP QEQRDGSFAK RVFEAEEADV IFVPFFATMS AEMQLGMAKG AFRKKVGNED 180 YERQRNVMDF LKSTDAWKKS GGRDHVFVLT DPVAMWHVKA EIAPAVLLVV DFGGWFRLDT 240 KSSNGSSPDM IQHTQVSVLK DVIVPYTHLL PRLHLSANKK RQTLLYFKGA KHRHRGGLVR 300 EKLWDLLVNE PDVIMEEGFP NATGKEQSIK GMRSSEFCLH PAGDTPTSCR LFDAIQSLCI 360 PVVVSDNIEL PFEDMVDYSE FSVFVAVNDA LKPNWLVKHL RTIPEEQRNR FRLYMARVQS 420 VFEYENGHPG GIGPVPPDGA VNHIWRKVHQ KLPMIKEAIA RERRKPKGVT VPLRCHCT* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-60 | 58 | 403 | 358 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 43 | 477 | 38 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 9 | 478 | 16 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 10 | 478 | 13 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 39 | 478 | 8 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 50 | 478 | 47 | 478 | catalytic, putative [Ricinus communis] |