Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.237620.1 |
Family | GT47 |
Protein Properties | Length: 333 Molecular Weight: 38139.9 Isoelectric Point: 7.9042 |
Chromosome | Chromosome/Scaffold: 02023 Start: 423894 End: 427017 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 3 | 283 | 0 |
KLLKIYVYKEGEPPMFHGGPCKSIYSTEGRFIHEMEKGNLYTTNDPDQALLYFLPFSVVNLVQYLYVPNSHEVNAIGTAITDYINVISNKHPFWDRSLGA DHFMLSCHDWGPRTTSFVPLLFNNSIRVLCNANVSEGFRPSKDASFPEIHLRTGEIDGLLGGLSPSRRSVLAFFAGRLHGHIRYLLLQEWKEKDEDVLVY DELPSGISYDSMLKKSRFCLCPSGYEVASPRVVEAIYAECVPVLISESYVPPFSDVLNWNSFAVQIQVKDIPNIKKILNGI |
Full Sequence |
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Protein Sequence Length: 333 Download |
MEKLLKIYVY KEGEPPMFHG GPCKSIYSTE GRFIHEMEKG NLYTTNDPDQ ALLYFLPFSV 60 VNLVQYLYVP NSHEVNAIGT AITDYINVIS NKHPFWDRSL GADHFMLSCH DWGPRTTSFV 120 PLLFNNSIRV LCNANVSEGF RPSKDASFPE IHLRTGEIDG LLGGLSPSRR SVLAFFAGRL 180 HGHIRYLLLQ EWKEKDEDVL VYDELPSGIS YDSMLKKSRF CLCPSGYEVA SPRVVEAIYA 240 ECVPVLISES YVPPFSDVLN WNSFAVQIQV KDIPNIKKIL NGISQTQYLR MQRRVKQVQR 300 HFVLNGTPKR FDAFHMILHS IWLRRLNIHI QD* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 5.0e-65 | 1 | 283 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAU04753.1 | 0 | 1 | 332 | 12 | 343 | EXO [Cucumis melo] |
EMBL | CBI28483.1 | 0 | 1 | 332 | 85 | 416 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002264076.1 | 0 | 1 | 332 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002320538.1 | 0 | 1 | 332 | 1 | 332 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002524591.1 | 0 | 1 | 332 | 173 | 504 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DT001362 | 234 | 17 | 250 | 0 |
EG631371 | 249 | 84 | 332 | 0 |
GW864815 | 305 | 17 | 320 | 0 |
CX643922 | 246 | 87 | 332 | 0 |
GO363500 | 276 | 30 | 304 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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