Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.249320.1 |
Family | GT47 |
Protein Properties | Length: 385 Molecular Weight: 44948.9 Isoelectric Point: 8.9688 |
Chromosome | Chromosome/Scaffold: 02209 Start: 51703 End: 55243 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 51 | 335 | 0 |
KKRLKIWTYKEGEQPLVHDGPMKHIYSIEGHFIDEMDSGKSPFSAHEPEEAQVFFLPISIVYIVDYIYKPITTYARDRLVRIFTDYVRVVANKYPYWNRT RGADHFMVSCHDWAPEVTKEDPNLFKYFIRVLCNANTSEGFNPMRDASLPEINLPPTFHLNLPRLGQPPQNRSILAFFAGGAHGFIRHILMQHWKDKDHE IQVHEYLPPSQNYTELIDRSKFCLCPSGYEVASPRLVEAIHGGCVPVVISDYYSLPFDDVLDWSKFSMRIPSERIPEIKTILRGV |
Full Sequence |
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Protein Sequence Length: 385 Download |
MIEEGLAEAR AAIRLAIVTR NYTSEKEESF IPRGRVYRNA YAFHQSHIEM KKRLKIWTYK 60 EGEQPLVHDG PMKHIYSIEG HFIDEMDSGK SPFSAHEPEE AQVFFLPISI VYIVDYIYKP 120 ITTYARDRLV RIFTDYVRVV ANKYPYWNRT RGADHFMVSC HDWAPEVTKE DPNLFKYFIR 180 VLCNANTSEG FNPMRDASLP EINLPPTFHL NLPRLGQPPQ NRSILAFFAG GAHGFIRHIL 240 MQHWKDKDHE IQVHEYLPPS QNYTELIDRS KFCLCPSGYE VASPRLVEAI HGGCVPVVIS 300 DYYSLPFDDV LDWSKFSMRI PSERIPEIKT ILRGVSMKKY LKLQRGVMKV QRHFEIHRPA 360 KAFDMFHMVL HSVWLRRLNV KLTH* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-61 | 50 | 335 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21065.1 | 0 | 3 | 382 | 19 | 400 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 2 | 384 | 91 | 477 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197526.4 | 0 | 1 | 382 | 26 | 407 | catalytic [Arabidopsis thaliana] |
Swiss-Prot | Q3E9A4 | 0 | 1 | 382 | 84 | 465 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002263848.1 | 0 | 2 | 384 | 10 | 396 | PREDICTED: hypothetical protein [Vitis vinifera] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EC939466 | 270 | 19 | 283 | 0 |
GE475605 | 301 | 88 | 385 | 0 |
FD507587 | 229 | 93 | 321 | 0 |
CO983212 | 232 | 152 | 383 | 0 |
FE523338 | 307 | 20 | 324 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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