Basic Information | |
---|---|
Species | Cucumis sativus |
Cazyme ID | Cucsa.260230.1 |
Family | GT47 |
Protein Properties | Length: 413 Molecular Weight: 47221.1 Isoelectric Point: 8.8705 |
Chromosome | Chromosome/Scaffold: 02229 Start: 6544029 End: 6554890 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 88 | 365 | 0 |
ESKFKVYIYPDGDPNTFYQTPRKLTGKYASEGYFFQNIRESRFRTEDPDQAHLFFIPISCHKMRGKGTSYENMTVIVQNYVEGLISKYPYWNRTLGADHF FVTCHDVGVRASEGLPFLIKNAIRVVCSPSYDVGFIPHKDVALPQVLQPFALPAGGNDTENRTTLGFWAGHRNSKIRVILARVWENDTELDISNNRISRA TGHLLYQKRFYKTKFCICPGGSQVNSARIADSIHYGCVPVILSDYYDLPFNDILDWRKFSVIVKERDVYQLKQILKDI |
Full Sequence |
---|
Protein Sequence Length: 413 Download |
MSALKHPFQL ASSSSSPLCS LRASLLTLAV LTLLSFTYLS FTSLHSSPPS SSSQLPVKLG 60 ALNDAADAEI SDVYHSPQVF RLNYADMESK FKVYIYPDGD PNTFYQTPRK LTGKYASEGY 120 FFQNIRESRF RTEDPDQAHL FFIPISCHKM RGKGTSYENM TVIVQNYVEG LISKYPYWNR 180 TLGADHFFVT CHDVGVRASE GLPFLIKNAI RVVCSPSYDV GFIPHKDVAL PQVLQPFALP 240 AGGNDTENRT TLGFWAGHRN SKIRVILARV WENDTELDIS NNRISRATGH LLYQKRFYKT 300 KFCICPGGSQ VNSARIADSI HYGCVPVILS DYYDLPFNDI LDWRKFSVIV KERDVYQLKQ 360 ILKDISDIEF IKLHKNLMQV QKHFQWNSPP IKYDAFHMVM YDLWLRHHVI KY* 420 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-60 | 87 | 365 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 20 | 412 | 10 | 409 | unknown [Glycine max] |
RefSeq | NP_195517.1 | 0 | 8 | 412 | 9 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 1 | 412 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 18 | 412 | 1 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 7 | 412 | 3 | 406 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
EH770778 | 275 | 103 | 377 | 0 |
JG847451 | 273 | 64 | 336 | 0 |
GO268625 | 269 | 87 | 355 | 0 |
EX317869 | 278 | 112 | 389 | 0 |
EG459159 | 264 | 150 | 413 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|