| Basic Information | |
|---|---|
| Species | Cucumis sativus |
| Cazyme ID | Cucsa.316820.1 |
| Family | GT47 |
| Protein Properties | Length: 511 Molecular Weight: 58741.5 Isoelectric Point: 9.235 |
| Chromosome | Chromosome/Scaffold: 03050 Start: 43635 End: 46074 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 179 | 461 | 0 |
| EKMLKVYVYDEGEKPIFHQPILTGIYASEGWFMKLLEDNKKFVVKDPEKAHLFYLPFSSQFLRSAFGNKFRNKRDLQKPLKNYIDVIGKKYRFWNKNGGS DHFLVACHDWAPKLTKRLVKNCIRALCNANGAGDFEIGKDTSLPVTFVHSTEDLITKIGGKPPSERTTLAFFAGSMHGYLRPILLHYWENKEPDMMIVGP MPNSIEGKNAYMEQMKSSKYCICARGYQVHSPRVIEAILNECIPVIISDNYVPPLFEVLNWESFSVFVKEREIPNLRDILLSI | |||
| Full Sequence |
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| Protein Sequence Length: 511 Download |
| MKGDVLENSN MTADEAKANS SPGMNEVKNQ IMVVPNQGTM NNSIKKVDQT YSDISVIPNT 60 SSDQKEKIKN SSEELETNDR IELVKKGSFV FNDKMVGPDV STLNGPFISI SQIYSKLSRA 120 HKSACSKRLQ CRQTSRRDHE LHYARLEIEN ASVLRSTPEI SSSVFRNISM FTRSYELMEK 180 MLKVYVYDEG EKPIFHQPIL TGIYASEGWF MKLLEDNKKF VVKDPEKAHL FYLPFSSQFL 240 RSAFGNKFRN KRDLQKPLKN YIDVIGKKYR FWNKNGGSDH FLVACHDWAP KLTKRLVKNC 300 IRALCNANGA GDFEIGKDTS LPVTFVHSTE DLITKIGGKP PSERTTLAFF AGSMHGYLRP 360 ILLHYWENKE PDMMIVGPMP NSIEGKNAYM EQMKSSKYCI CARGYQVHSP RVIEAILNEC 420 IPVIISDNYV PPLFEVLNWE SFSVFVKERE IPNLRDILLS IPEENYRAMH SRVKMVQQHF 480 LWHEKPAKYD AFHMILHSIW YTRVFQIKSN * |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 2.0e-64 | 178 | 461 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08970.1 | 0 | 105 | 509 | 151 | 558 | unnamed protein product [Arabidopsis thaliana] |
| EMBL | CBI28021.1 | 0 | 5 | 508 | 161 | 663 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002280595.1 | 0 | 5 | 508 | 159 | 661 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002281263.1 | 0 | 54 | 508 | 215 | 667 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002514249.1 | 0 | 178 | 509 | 1 | 333 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| ES808098 | 337 | 145 | 480 | 0 |
| JG217834 | 296 | 220 | 509 | 0 |
| GO261722 | 258 | 203 | 460 | 0 |
| EX272008 | 266 | 227 | 492 | 0 |
| EX272008 | 45 | 466 | 510 | 0.26 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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