y
Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.320620.1 |
Family | GT47 |
Protein Properties | Length: 473 Molecular Weight: 54511.4 Isoelectric Point: 6.8677 |
Chromosome | Chromosome/Scaffold: 03080 Start: 397876 End: 399850 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 38 | 396 | 0 |
CDDRWIHIRSLPSRFNLDLLSNCSEYPIFDDFCPYLANHGLGHKTYNRSHSWYRTDPSMLELIFHRRMLEYPCLTSDPDSADAIYLPYYTSIDALRYLYG SQVNSSAEHGLELFEFLSRNQPEIWNRRLGHDHFFVMARPAWDFSQPLENDPPIWGTSLLELPQFFNVTALTYEGRAWPWQEQAIPYPTSFHPPNLAFLE SWLQRVKRSKRSTLMLFAGGGGISATPNIRRSIRIECQSANDDDDVTNSRKGRNGDASLYSKLCEVVDCSNGICEHDPVRYFRPMLQATFCLQPPGDTPT RRSTFDGILAGCIPVFFEDLSAKSQYKWHLPEETFEEFAVTIPKEDVVFKGIKILDVLM |
Full Sequence |
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Protein Sequence Length: 473 Download |
MACKPIPVFF LFFYFFSFFI QLYFAQHISP PEILPKHCDD RWIHIRSLPS RFNLDLLSNC 60 SEYPIFDDFC PYLANHGLGH KTYNRSHSWY RTDPSMLELI FHRRMLEYPC LTSDPDSADA 120 IYLPYYTSID ALRYLYGSQV NSSAEHGLEL FEFLSRNQPE IWNRRLGHDH FFVMARPAWD 180 FSQPLENDPP IWGTSLLELP QFFNVTALTY EGRAWPWQEQ AIPYPTSFHP PNLAFLESWL 240 QRVKRSKRST LMLFAGGGGI SATPNIRRSI RIECQSANDD DDVTNSRKGR NGDASLYSKL 300 CEVVDCSNGI CEHDPVRYFR PMLQATFCLQ PPGDTPTRRS TFDGILAGCI PVFFEDLSAK 360 SQYKWHLPEE TFEEFAVTIP KEDVVFKGIK ILDVLMGIPR ARIRRMREKV IELIPSVMYR 420 KHGSSLGLRT KKDAVDIAIE GTLQKIGMRV KELDLEVNNK RVFVTESGVG EV* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-53 | 37 | 385 | 361 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 38 | 450 | 37 | 435 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 38 | 456 | 33 | 444 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 38 | 450 | 29 | 429 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 1 | 456 | 1 | 438 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 1 | 451 | 1 | 450 | catalytic, putative [Ricinus communis] |