Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.332740.1 |
Family | GT47 |
Protein Properties | Length: 465 Molecular Weight: 53039.7 Isoelectric Point: 8.2565 |
Chromosome | Chromosome/Scaffold: 03264 Start: 539031 End: 543222 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 72 | 388 | 0 |
PVKIYLYDVPTRFTYGVIENHGIARGGKPVPDVTDLKYPGHQHMAEWFLFTDLLRPESERIGSAVVRVFDPEEADLFYVPFFSSLSLIVNPIRPATGSDQ QQRKLVYSDEETQDAFMEWLEKQEYWKRSNGRDHVIIAQDPNALYRLIDRVKNSILLVSDFGRLRADQASLVKDVIVPYSHRINTYTGDIGVENRKTLLF FMGNRYRKEGGKIRDMLFNILELEQDVIIKHGTQSRESRRAATHGMHTSKFCLNPAGDTPSACRLFDSVVSLCVPVIVSDSIELPFEDVIDYSKIAVFFD SVSAVKPEFLISKLRRI |
Full Sequence |
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Protein Sequence Length: 465 Download |
MARKSSLLKR TLASLCFILA LYAIINTFIS STATLKLDRS FPFSSANSVI VSDEFSSQDT 60 DLLNSSGKSL SPVKIYLYDV PTRFTYGVIE NHGIARGGKP VPDVTDLKYP GHQHMAEWFL 120 FTDLLRPESE RIGSAVVRVF DPEEADLFYV PFFSSLSLIV NPIRPATGSD QQQRKLVYSD 180 EETQDAFMEW LEKQEYWKRS NGRDHVIIAQ DPNALYRLID RVKNSILLVS DFGRLRADQA 240 SLVKDVIVPY SHRINTYTGD IGVENRKTLL FFMGNRYRKE GGKIRDMLFN ILELEQDVII 300 KHGTQSRESR RAATHGMHTS KFCLNPAGDT PSACRLFDSV VSLCVPVIVS DSIELPFEDV 360 IDYSKIAVFF DSVSAVKPEF LISKLRRISE ERILDYQREM KKIKRYFEYT DSNGTVNEIW 420 RQVSQKLPLI KLMINREKRV IHRDGDEPNC SCLCSNQTGI RARL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-73 | 69 | 388 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 1 | 464 | 1 | 461 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002276440.1 | 0 | 1 | 464 | 34 | 494 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318294.1 | 0 | 77 | 460 | 1 | 378 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 1 | 459 | 1 | 452 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 1 | 460 | 1 | 448 | catalytic, putative [Ricinus communis] |