Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.340400.1 |
Family | GT47 |
Protein Properties | Length: 467 Molecular Weight: 53264.5 Isoelectric Point: 9.3199 |
Chromosome | Chromosome/Scaffold: 03356 Start: 2860926 End: 2863313 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 139 | 415 | 0 |
KSFKIYVYPHKRSDPFARSLLPENFEPHGNYASESYFKKSLIKSHFITNDPKEADFFFLPFSITGLRNDRRVSVSGIPNFIRDYIFDVSHKYPYWNRTGG ADHFYVACHSVGRSAMDKSSEAKSSIVQVVCSSSYFLTGYISHKDAALPQIWPRKEDPSNLASSKRTRLAFFAGAMNSPTRQALVQVWGKDSEIFAYSGR LKTPYADELLRSKFCLHVKGFEVNTARVGDSIFYGCVPVIIANYYDLPFGDILNWKSFSIVVTTSDIPRLKEILKGI |
Full Sequence |
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Protein Sequence Length: 467 Download |
MPQSPFPWRS SSSSSTSSSS TNWFRGLFFI PTCLALNSFL FILFYISSTS TPNPFPSQIP 60 SHFSDSSSRY VSSLNLSITT LRVAQKVSLP DDNGGPPLPQ FQTQPFPPLP SFGKRIHEQA 120 EGVFHDEELF LEDYKEMNKS FKIYVYPHKR SDPFARSLLP ENFEPHGNYA SESYFKKSLI 180 KSHFITNDPK EADFFFLPFS ITGLRNDRRV SVSGIPNFIR DYIFDVSHKY PYWNRTGGAD 240 HFYVACHSVG RSAMDKSSEA KSSIVQVVCS SSYFLTGYIS HKDAALPQIW PRKEDPSNLA 300 SSKRTRLAFF AGAMNSPTRQ ALVQVWGKDS EIFAYSGRLK TPYADELLRS KFCLHVKGFE 360 VNTARVGDSI FYGCVPVIIA NYYDLPFGDI LNWKSFSIVV TTSDIPRLKE ILKGINDEEY 420 ARLQSNVLKV RKHFKWHSSP VDYDTFHMVM YQLWLRRTSV RLPLLD* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-65 | 137 | 415 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD28410.1 | 0 | 30 | 466 | 26 | 485 | Exostosin-like [Medicago truncatula] |
EMBL | CBI39073.1 | 0 | 79 | 465 | 55 | 448 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 79 | 464 | 55 | 445 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325425.1 | 0 | 137 | 464 | 1 | 324 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002525728.1 | 0 | 137 | 462 | 1 | 326 | catalytic, putative [Ricinus communis] |