| Basic Information | |
|---|---|
| Species | Cucumis sativus |
| Cazyme ID | Cucsa.359580.8 |
| Family | GH47 |
| Protein Properties | Length: 546 Molecular Weight: 62130 Isoelectric Point: 4.9757 |
| Chromosome | Chromosome/Scaffold: 03588 Start: 459795 End: 467812 |
| Description | alpha-mannosidase 2 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH47 | 84 | 513 | 0 |
| IHAWNSYEKYAWGQDELQPQSKSGINSFGGLGATIVDSLDTLYIMGLDEQFQKAKEWVANSLDFNKNYDASVFETTIRVVGGLLSAYDLSGDKLFLDKAV DIADRLLPAWDTPSGIPYNFINLVDGRPHNPSWTGGFSILADAGTEQLEFISLSQRTGDPKYQQKVENVITQLNKNFPDDGLLPIYIDPNEGKGSHATIT FGAMGDSFYEYLLKVWIHGNKTSAVKHYREMWEKSMKGLSSLVRRTTPSAFTYICEKSGSSLSDKMDELACFAPGMIALGSSGYDSEESKKFLTLAEELA WTCYNFYQTTPTKLAGENYFFYSGEDMSVGTSWNILRPETVESLFYLWRLTGNKTYKEWGWNIFQAFEKNSRVESGYVGLKDVNTGVKDNMMQSFFLAET LKYIYLLFTPPSVIPLDEWVFNTEAHPLRI | |||
| Full Sequence |
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| Protein Sequence Length: 546 Download |
| MARTRSSTSK WSLLVWDRQT LLREHEDELA KLKSEVVRLK SLVEEDNDKT MNGIAARVHE 60 EAKEEEVDDP IDAERREKVK EAAIHAWNSY EKYAWGQDEL QPQSKSGINS FGGLGATIVD 120 SLDTLYIMGL DEQFQKAKEW VANSLDFNKN YDASVFETTI RVVGGLLSAY DLSGDKLFLD 180 KAVDIADRLL PAWDTPSGIP YNFINLVDGR PHNPSWTGGF SILADAGTEQ LEFISLSQRT 240 GDPKYQQKVE NVITQLNKNF PDDGLLPIYI DPNEGKGSHA TITFGAMGDS FYEYLLKVWI 300 HGNKTSAVKH YREMWEKSMK GLSSLVRRTT PSAFTYICEK SGSSLSDKMD ELACFAPGMI 360 ALGSSGYDSE ESKKFLTLAE ELAWTCYNFY QTTPTKLAGE NYFFYSGEDM SVGTSWNILR 420 PETVESLFYL WRLTGNKTYK EWGWNIFQAF EKNSRVESGY VGLKDVNTGV KDNMMQSFFL 480 AETLKYIYLL FTPPSVIPLD EWVFNTEAHP LRIVTRKEGR DIERILDEKR KPFIRLRSRK 540 EGRSD* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01532 | Glyco_hydro_47 | 0 | 85 | 513 | 448 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| PTZ00470 | PTZ00470 | 0 | 44 | 513 | 484 | + glycoside hydrolase family 47 protein; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF16414.1 | 0 | 56 | 544 | 89 | 577 | AF126550_1 mannosyl-oligosaccharide 1,2-alpha-mannosidase [Glycine max] |
| GenBank | AAK92711.1 | 0 | 12 | 543 | 40 | 568 | putative mannosidase [Arabidopsis thaliana] |
| EMBL | CBI18472.1 | 0 | 1 | 543 | 1 | 571 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_175570.1 | 0 | 12 | 543 | 39 | 556 | mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Arabidopsis thaliana] |
| RefSeq | NP_566675.1 | 0 | 12 | 543 | 40 | 568 | mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 66 | 523 | 8 | 474 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 70 | 515 | 4 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 70 | 515 | 4 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 70 | 515 | 4 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 70 | 515 | 82 | 536 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
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| Hit | Length | Start | End | EValue |
| HO780776 | 492 | 12 | 480 | 0 |
| CU615093 | 322 | 222 | 543 | 0 |
| DY974119 | 307 | 143 | 449 | 0 |
| GW895275 | 284 | 218 | 500 | 0 |
| HO780776 | 74 | 471 | 544 | 3e-24 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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