Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.360570.1 |
Family | AA3 |
Protein Properties | Length: 589 Molecular Weight: 64671.1 Isoelectric Point: 9.2079 |
Chromosome | Chromosome/Scaffold: 03588 Start: 1191147 End: 1196485 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 52 | 577 | 0 |
RKGGYDYIIVGGGTAGCPLAATLSQNFSVLLLERGGVPFTNANVSFLGNFHIGLADTSPTSASQAFASTDGVINARARVLGGGSAINAGFYTRASTRFIK RVGWDERLVNESYSWVENRIVHRPELADWQKAFTDSMLDVGISPFNGFTYDHLYGTKVGGTIFDRFGRRHTTAELLASGNPDKLTVLVHATVQRLIFDTT DGKKPKAIGVVFKDDIGNQHEVFLSSNRQSEVIMSSGAIGTPQMLLLSGIGPRADLEKWNISMVLDNEFVGKNMADNPLNAIFVPSNRPVKQSLIQAVGI TKRGVYIESSSGFGQSGESIHCHHGLMSAEIGQLSTIPPKQRTPEAIQAYIKSKRDLPHEAFKGGFVLEKIAYPISRGQLSLINTNVDDNPAVTFNYFGH PYDLHRCVEGIRMVAKIVESKCFTNFTQCDEETLDKLLNISVKANINLIPKHTNDTKSLEQFCKDTVITIWHYHGGCLVDKVVSHDLKVLGVTRLRIVDG STLSESPGTNPQATVMMMGRYMGLKI |
Full Sequence |
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Protein Sequence Length: 589 Download |
MALAGTVKLF LFLVLFTLLH LLSSCQGREN WIKSRYPFIK RASSFYRDGH ERKGGYDYII 60 VGGGTAGCPL AATLSQNFSV LLLERGGVPF TNANVSFLGN FHIGLADTSP TSASQAFAST 120 DGVINARARV LGGGSAINAG FYTRASTRFI KRVGWDERLV NESYSWVENR IVHRPELADW 180 QKAFTDSMLD VGISPFNGFT YDHLYGTKVG GTIFDRFGRR HTTAELLASG NPDKLTVLVH 240 ATVQRLIFDT TDGKKPKAIG VVFKDDIGNQ HEVFLSSNRQ SEVIMSSGAI GTPQMLLLSG 300 IGPRADLEKW NISMVLDNEF VGKNMADNPL NAIFVPSNRP VKQSLIQAVG ITKRGVYIES 360 SSGFGQSGES IHCHHGLMSA EIGQLSTIPP KQRTPEAIQA YIKSKRDLPH EAFKGGFVLE 420 KIAYPISRGQ LSLINTNVDD NPAVTFNYFG HPYDLHRCVE GIRMVAKIVE SKCFTNFTQC 480 DEETLDKLLN ISVKANINLI PKHTNDTKSL EQFCKDTVIT IWHYHGGCLV DKVVSHDLKV 540 LGVTRLRIVD GSTLSESPGT NPQATVMMMG RYMGLKILMD RLGKKGGT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01810 | betA | 3.0e-19 | 57 | 328 | 306 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
pfam05199 | GMC_oxred_C | 9.0e-25 | 425 | 570 | 151 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR03970 | Rv0697 | 3.0e-26 | 57 | 570 | 561 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
COG2303 | BetA | 2.0e-41 | 51 | 581 | 591 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 23 | 587 | 570 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN78644.1 | 0 | 22 | 583 | 21 | 606 | hypothetical protein [Vitis vinifera] |
EMBL | CBI35951.1 | 0 | 22 | 587 | 21 | 592 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002275841.1 | 0 | 15 | 587 | 7 | 583 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002329018.1 | 0 | 20 | 587 | 18 | 590 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 34 | 587 | 39 | 596 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 51 | 581 | 22 | 517 | B Chain B, Crystal Structure Of Plant Cell Wall Invertase In Complex With A Specific Protein Inhibitor |
PDB | 3gdp_A | 0 | 51 | 581 | 22 | 517 | B Chain B, Crystal Structure Of Plant Cell Wall Invertase In Complex With A Specific Protein Inhibitor |
PDB | 3gdn_B | 0 | 51 | 581 | 22 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 51 | 581 | 22 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 51 | 581 | 22 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |