| Basic Information | |
|---|---|
| Species | Cucumis sativus |
| Cazyme ID | Cucsa.363720.1 |
| Family | GT1 |
| Protein Properties | Length: 545 Molecular Weight: 60483.7 Isoelectric Point: 6.947 |
| Chromosome | Chromosome/Scaffold: 03611 Start: 1333374 End: 1349226 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT1 | 175 | 502 | 0 |
| TEPDPDTGMPFRAQAIIANAPAYGCACLIWVAGHTHVAEALHVPLHIFFTMPWTPTNEFPHPLARVPQNTGYWLSYIIVELLIWWGIRGSINEFRRKKLN LPPIAYFSTYRGSISHLPTAYMWSPSVVPKPKDWGPLVDVVGYCFLDRGFKYQPEELVLKWIKKGTKPIYVGFGSMPLAEPQRTTHIILEALKDTGQRGI LDRGLGGLGNCTELPEDVLLIQDCPHDWLFRHCSAVVHHGGAGTTSTGLRAGCPTTIVPFFGDQFFWGETTHQKGLGLAPIPISQLNPTNLSNAINFMLQ PEVKRRATEIAKIIDSEDGVVAAVNAFH | |||
| Full Sequence |
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| Protein Sequence Length: 545 Download |
| MTEWIGTQRP DLKFDELSGD KQKQLVADLV KIQRDGTVEV DIENAPAASE LLKLHPTLEG 60 SSPIVDDVVS ESKKLIPRLK IAILVVGTRG DVQPFLAIAR RLQEFGHHVR LATHTNFSNF 120 VRSAGVNFYP LAGDSRELAE YMTRNRGFIP SGPGEISVQR KHLKVIIEST LPACTEPDPD 180 TGMPFRAQAI IANAPAYGCA CLIWVAGHTH VAEALHVPLH IFFTMPWTPT NEFPHPLARV 240 PQNTGYWLSY IIVELLIWWG IRGSINEFRR KKLNLPPIAY FSTYRGSISH LPTAYMWSPS 300 VVPKPKDWGP LVDVVGYCFL DRGFKYQPEE LVLKWIKKGT KPIYVGFGSM PLAEPQRTTH 360 IILEALKDTG QRGILDRGLG GLGNCTELPE DVLLIQDCPH DWLFRHCSAV VHHGGAGTTS 420 TGLRAGCPTT IVPFFGDQFF WGETTHQKGL GLAPIPISQL NPTNLSNAIN FMLQPEVKRR 480 ATEIAKIIDS EDGVVAAVNA FHHHLPSELP LPPASEEDED FANPLQWLLL KVEKWCCVPC 540 GLRL* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01426 | MGT | 1.0e-10 | 90 | 497 | 428 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
| pfam03033 | Glyco_transf_28 | 1.0e-26 | 81 | 234 | 154 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| COG1819 | COG1819 | 6.0e-43 | 78 | 499 | 429 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| cd03784 | GT1_Gtf_like | 1.0e-114 | 80 | 501 | 422 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABC96116.1 | 0 | 1 | 541 | 169 | 700 | sterol glucosyltransferase [Withania somnifera] |
| EMBL | CBI18214.1 | 0 | 1 | 541 | 165 | 697 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265312.1 | 0 | 1 | 541 | 149 | 681 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002302172.1 | 0 | 7 | 540 | 86 | 615 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524293.1 | 0 | 7 | 540 | 51 | 577 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 2e-27 | 79 | 497 | 1 | 374 | A Chain A, Crystal Structure Of The Putative Acetylxylan Esterase From Clostridium Acetobutylicum, Northeast Structural Genomics Target Car6 |
| PDB | 3h4i_A | 2e-27 | 79 | 497 | 1 | 374 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1iir_A | 4e-23 | 79 | 497 | 1 | 391 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 1rrv_B | 6e-21 | 79 | 488 | 1 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 6e-21 | 79 | 488 | 1 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DT547914 | 331 | 97 | 427 | 0 |
| HO801427 | 429 | 109 | 530 | 0 |
| GT172550 | 311 | 57 | 367 | 0 |
| HO801427 | 29 | 79 | 107 | 0.0003 |
| GT172550 | 57 | 387 | 440 | 0.7 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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