Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.385750.1 |
Family | GT47 |
Protein Properties | Length: 460 Molecular Weight: 53378.2 Isoelectric Point: 10.038 |
Chromosome | Chromosome/Scaffold: 03904 Start: 1015676 End: 1017681 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 105 | 403 | 0 |
EVKVFVYDLPPKYNVEWLSNERCSNHLFASEVAIHRALLNSHYRTFDPLEADFFFVPVYVSCNFSTVNGFPAIGHARSLISSAVSHISSHYSFWNRTNGS DHVFVASHDFASCFHTMEHVAIADGVPSFLKNSIILQTFGVKYKHPCQDVEHVVIPPYIPPESIENTLERSPVTGRRDIFAFFRGKMEMNPKNVSGRFYS KKVRTMIWRKFNGDRRFYLQRHRFPGYQSEIVRSVFCLCPLGWAPWSPRLVESVALGCVPVIIADGIRLPFPSAVNWPEISITVAEKDIGKLGRILDHV |
Full Sequence |
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Protein Sequence Length: 460 Download |
MVESKVFPRR KGFYVRMRLF PHKNCRAQEK SFFIRYYKWL LWVSLSLYFF TSYYISHNHK 60 SHGTSDRMPR THLSNSKSFP SRALIETSNT TFLRQVQQNQ ELLEEVKVFV YDLPPKYNVE 120 WLSNERCSNH LFASEVAIHR ALLNSHYRTF DPLEADFFFV PVYVSCNFST VNGFPAIGHA 180 RSLISSAVSH ISSHYSFWNR TNGSDHVFVA SHDFASCFHT MEHVAIADGV PSFLKNSIIL 240 QTFGVKYKHP CQDVEHVVIP PYIPPESIEN TLERSPVTGR RDIFAFFRGK MEMNPKNVSG 300 RFYSKKVRTM IWRKFNGDRR FYLQRHRFPG YQSEIVRSVF CLCPLGWAPW SPRLVESVAL 360 GCVPVIIADG IRLPFPSAVN WPEISITVAE KDIGKLGRIL DHVAGSNLTT IQKNLWDPRN 420 RRALLFHNQV EDGDATWQVI GALSEKLDRS YRRWRVLKQ* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-65 | 109 | 400 | 299 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33322.1 | 0 | 22 | 456 | 7 | 439 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
GenBank | ABI64067.1 | 0 | 22 | 459 | 7 | 442 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
RefSeq | XP_002275679.1 | 0 | 1 | 448 | 1 | 441 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002314302.1 | 0 | 10 | 459 | 14 | 462 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523710.1 | 0 | 9 | 459 | 10 | 461 | transferase, putative [Ricinus communis] |