Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.385790.1 |
Family | GH29 |
Protein Properties | Length: 535 Molecular Weight: 59909.5 Isoelectric Point: 4.9353 |
Chromosome | Chromosome/Scaffold: 03904 Start: 1031790 End: 1034361 |
Description | alpha-L-fucosidase 1 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH29 | 64 | 360 | 0 |
SQIQWQLGNMALFLHFGPNTFTDSEWGTGHVHPSVFNPINLDAAQWVRVAKDAGFSRIILTAKHHDGFCLWPSEYTNYSVSSSPWRNGKGDVLGELAKAA KEAGLGLGLYLSPWDRHESCYGKTLEYNEFYLGQMTELLTRYGEIKEVWLDGAKGEGEKDMEYFFDSWFSLIHQLQPGAVIFSDAGPDCRWIGDEAGVAK PTCWSLFNSSSAKIGGTDSRYSGEGDPYGHDWIPAECDVSIRPGWFWHPSEVPKSARTLLDIYYKSAGRNCLLLLNVPPNSSGLISDEDVQVLQEFT |
Full Sequence |
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Protein Sequence Length: 535 Download |
MKNHNIIFFT NCNFPKPFSL LNSISSFSLF FLLSLFLQPI SSSSSSSLIN NPPPLPILPI 60 PSASQIQWQL GNMALFLHFG PNTFTDSEWG TGHVHPSVFN PINLDAAQWV RVAKDAGFSR 120 IILTAKHHDG FCLWPSEYTN YSVSSSPWRN GKGDVLGELA KAAKEAGLGL GLYLSPWDRH 180 ESCYGKTLEY NEFYLGQMTE LLTRYGEIKE VWLDGAKGEG EKDMEYFFDS WFSLIHQLQP 240 GAVIFSDAGP DCRWIGDEAG VAKPTCWSLF NSSSAKIGGT DSRYSGEGDP YGHDWIPAEC 300 DVSIRPGWFW HPSEVPKSAR TLLDIYYKSA GRNCLLLLNV PPNSSGLISD EDVQVLQEFT 360 MIRDSIFSYN LAENALVDGS STRGDDEDVR FTPANVLKEG IYTYWAPAEN QPTWALYLNL 420 QDFISFNVLL IQEPIHMGQR IIEFHFDILN DEGVWSTVVT GTTVGYRRIL RFPTVESQFL 480 RLVIEKSRAD PLVSYLGIHL DNFSHLDSHL GKTSINGSEI RRQITLNNSE ISAV* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
smart00812 | Alpha_L_fucos | 6.0e-27 | 99 | 359 | 282 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
pfam01120 | Alpha_L_fucos | 1.0e-27 | 99 | 359 | 278 | + Alpha-L-fucosidase. | ||
COG3669 | COG3669 | 6.0e-54 | 67 | 494 | 443 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] |
Gene Ontology | |
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GO Term | Description |
GO:0004560 | alpha-L-fucosidase activity |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_180377.2 | 0 | 51 | 515 | 28 | 493 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
Swiss-Prot | Q8GW72 | 0 | 51 | 515 | 28 | 493 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
RefSeq | XP_002276131.1 | 0 | 62 | 534 | 51 | 545 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002313533.1 | 0 | 62 | 504 | 15 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523703.1 | 0 | 62 | 534 | 64 | 542 | alpha-l-fucosidase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3ues_B | 0 | 61 | 494 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3ues_A | 0 | 61 | 494 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3mo4_B | 0 | 61 | 494 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
PDB | 3mo4_A | 0 | 61 | 494 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
PDB | 3uet_B | 0 | 61 | 494 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DY270181 | 287 | 65 | 351 | 0 |
DY291901 | 282 | 65 | 346 | 0 |
FC905625 | 277 | 65 | 341 | 0 |
DY272403 | 297 | 65 | 360 | 0 |
DY300194 | 286 | 90 | 375 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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