Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.A01384.1 |
Family | GT47 |
Protein Properties | Length: 560 Molecular Weight: 63097.2 Isoelectric Point: 7.8981 |
Chromosome | Chromosome/Scaffold: 1 Start: 22267564 End: 22269811 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 226 | 508 | 0 |
KLFKIYVYQEGEPPMFHDGPCKSIYSTEGRFIHEMERGHNMYRTTDPDEALVYFLPFSVVMLVQYLYEPGSHETHAIGHAVVDYIDVIAAKHPFWNRSLG ADHFMLSCHDWGPRTSSYVPNLFSKSIRVLCNANTSEGFDPFKDASLPEINLKTGEIFGLLGGPSPSRRGTLAFFAGRLHGHIRHLLLQEWKDKEDPDVR VYDELPRGVSYESMLRQSRYCLCPSGYEVASPRIVEAIYAECVPVLISDSYVPPFSDVLNWKAFSVQVQVKDIPNIKKLLMAI |
Full Sequence |
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Protein Sequence Length: 560 Download |
MGTSKAFSPA PSSPPRSSSS LLVLYLVVPV VLISAGLFAL AGNGSPSRVE LASPWKLRVA 60 FAGSRATAAL SALRPSDFPR AIESPWPLSY SEENQVAFAP ASVRMERTFV QNFLFLLFIL 120 DTLHGHALII LGSFACPFYQ APENEPPTEQ PEPDETVTVE EPARAVKRYS RFERLEASLS 180 QARSAIREAA LVRNLTSVHA DADYVPRGPI YRNANAFHRS YLEMEKLFKI YVYQEGEPPM 240 FHDGPCKSIY STEGRFIHEM ERGHNMYRTT DPDEALVYFL PFSVVMLVQY LYEPGSHETH 300 AIGHAVVDYI DVIAAKHPFW NRSLGADHFM LSCHDWGPRT SSYVPNLFSK SIRVLCNANT 360 SEGFDPFKDA SLPEINLKTG EIFGLLGGPS PSRRGTLAFF AGRLHGHIRH LLLQEWKDKE 420 DPDVRVYDEL PRGVSYESML RQSRYCLCPS GYEVASPRIV EAIYAECVPV LISDSYVPPF 480 SDVLNWKAFS VQVQVKDIPN IKKLLMAISP SQYLRMQRRV KQVQRHFVAN GPPRRYDVFH 540 MTVHSIWLRR LNIRITDSA* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-54 | 224 | 508 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAU04753.1 | 0 | 219 | 557 | 7 | 343 | EXO [Cucumis melo] |
EMBL | CBI28483.1 | 0 | 167 | 557 | 28 | 416 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002264076.1 | 0 | 224 | 557 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002320538.1 | 0 | 224 | 557 | 1 | 332 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002524591.1 | 0 | 152 | 557 | 102 | 504 | catalytic, putative [Ricinus communis] |