Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.B03487.1 |
Family | GT47 |
Protein Properties | Length: 337 Molecular Weight: 38573.1 Isoelectric Point: 8.7282 |
Chromosome | Chromosome/Scaffold: 2 Start: 59623342 End: 59627465 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 22 | 260 | 0 |
EAVRVLDPESADVFFVPFFSSLSFNTHGHNMTDPATEIDRELQIDLLEFLRQSKYWQRSGGRDHVIPMTHPNAFRFLREQVNASILIVADFGRFSKTVSN LNKDVVAPYVHVVDSFVDDDIVDPYGLRPLLLFFRGRTVRKDEGIVRAKLAKILAGYDDVHYERSIATVESIKKSTQGMRSSKFCLHPAGDTPSSCRLFD AIVSHCIPVIVSDQIELPYEDEIDYSQFSIFFSVKEALK |
Full Sequence |
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Protein Sequence Length: 337 Download |
MGSLLYDGDA GGGGGGGGGG REAVRVLDPE SADVFFVPFF SSLSFNTHGH NMTDPATEID 60 RELQIDLLEF LRQSKYWQRS GGRDHVIPMT HPNAFRFLRE QVNASILIVA DFGRFSKTVS 120 NLNKDVVAPY VHVVDSFVDD DIVDPYGLRP LLLFFRGRTV RKDEGIVRAK LAKILAGYDD 180 VHYERSIATV ESIKKSTQGM RSSKFCLHPA GDTPSSCRLF DAIVSHCIPV IVSDQIELPY 240 EDEIDYSQFS IFFSVKEALK PGYMVDQLRL FPKERWIEMW KQLRTISHHY EFQYPPKKED 300 AVDMLWRQVK HKVPRVKLAV HRNRRLKIPD WWGRRR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-42 | 24 | 260 | 245 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_176908.2 | 0 | 15 | 332 | 109 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 1 | 336 | 105 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 23 | 332 | 71 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002456855.1 | 0 | 13 | 333 | 112 | 432 | hypothetical protein SORBIDRAFT_03g044100 [Sorghum bicolor] |
RefSeq | XP_002512333.1 | 0 | 1 | 335 | 109 | 434 | catalytic, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3qd7_X | 0.0008 | 86 | 199 | 17 | 136 | X Chain X, Crystal Structure Of Ydal, A Stand-Alone Small Muts-Related Protein From Escherichia Coli |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EC955869 | 281 | 30 | 310 | 0 |
DT749776 | 263 | 74 | 336 | 0 |
GO041156 | 265 | 71 | 335 | 0 |
DY266782 | 269 | 1 | 269 | 0 |
FC916665 | 266 | 1 | 266 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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