Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.C01719.1 |
Family | GT47 |
Protein Properties | Length: 340 Molecular Weight: 39086.2 Isoelectric Point: 8.8744 |
Chromosome | Chromosome/Scaffold: 3 Start: 29112344 End: 29114318 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 4 | 291 | 0 |
ERRFKVYVYSEGEPPIVHDGPCKDIYTVEGRFIHEMEHGSAAARFGTRDPRRAHVYFMPFSVTRMVTYLYKPPTYDVTPLRRFVADYVQAVSAKYPFWNR TRGADHFMVACHDWGPHASLGDAHLYKNSIRALCNANASEGFNPQKDVSLPEIYLLDGNISPKLLSLPPPHVPRPLLTFFAGGLHGPIRPILLHHWKDKG DPDVRVYGYLPKHLDYYTLILQSKFCLCPSGHEVASPRIVEAIYAECVPVIISEHYVLPFSDVLNWDAFSVKVEVSEIPRLKEILKAV |
Full Sequence |
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Protein Sequence Length: 340 Download |
MEMERRFKVY VYSEGEPPIV HDGPCKDIYT VEGRFIHEME HGSAAARFGT RDPRRAHVYF 60 MPFSVTRMVT YLYKPPTYDV TPLRRFVADY VQAVSAKYPF WNRTRGADHF MVACHDWGPH 120 ASLGDAHLYK NSIRALCNAN ASEGFNPQKD VSLPEIYLLD GNISPKLLSL PPPHVPRPLL 180 TFFAGGLHGP IRPILLHHWK DKGDPDVRVY GYLPKHLDYY TLILQSKFCL CPSGHEVASP 240 RIVEAIYAEC VPVIISEHYV LPFSDVLNWD AFSVKVEVSE IPRLKEILKA VPEDEYRRLR 300 QGLKAVRRHF VLNQPAKRFD VFHMVLHSIW LRRLNLNLG* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-63 | 3 | 291 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 1 | 339 | 143 | 478 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 1 | 338 | 145 | 479 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 3 | 339 | 1 | 334 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 3 | 338 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 1 | 339 | 146 | 481 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DR923559 | 240 | 101 | 340 | 0 |
FE523338 | 271 | 2 | 272 | 0 |
GE475605 | 299 | 43 | 339 | 0 |
GO363500 | 280 | 33 | 312 | 0 |
GW864815 | 310 | 19 | 328 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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