Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.D02098.1 |
Family | GT47 |
Protein Properties | Length: 545 Molecular Weight: 62817.1 Isoelectric Point: 9.7241 |
Chromosome | Chromosome/Scaffold: 4 Start: 35091309 End: 35096281 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 207 | 492 | 0 |
ILKVYIYPDGRRPIFHQPHLRGIYASEGWFMKHMEGNRQFVTRDPEKAHLFYLSYSARQLQKELYVPDSHNTRPLSIFLRDHVNWIAAKYPFWNRTHGSD HFLVACHDWGPYTVNEHKELSKNTIKALCNADLSEGIFTAGRDVSLAETTIRNPRRPLRYVGGKRVSQRSILAFFAGNMHGRVRPTLLKFWQDKDEDMRI YGPLPNRVSRKMSYVEHMKSSKYCICPMGYEVNSPRIVEAIYYECVPVIIADNFVPPLNEVLDWSAFSVVVAEKDIPKLKEILLAI |
Full Sequence |
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Protein Sequence Length: 545 Download |
MRKFLPRIAL VLMGELFRRC IGKRIDWRKI FFLGAIMTLA GVLLPNIIFP YALDTWFFSP 60 PVTISAYAIL NGTTHLSETV NGATVEQSHL VLAAPVASVN ASTNLTQLES VEEEIPAKIN 120 ILEEEKILAS PLPFLASPPP PPSPPRKRYV SSSLQRDLWS LPPHEALVYA KKEIAHAPPV 180 TDDPDLYAPL FRNISVFKRS YELMEQILKV YIYPDGRRPI FHQPHLRGIY ASEGWFMKHM 240 EGNRQFVTRD PEKAHLFYLS YSARQLQKEL YVPDSHNTRP LSIFLRDHVN WIAAKYPFWN 300 RTHGSDHFLV ACHDWGPYTV NEHKELSKNT IKALCNADLS EGIFTAGRDV SLAETTIRNP 360 RRPLRYVGGK RVSQRSILAF FAGNMHGRVR PTLLKFWQDK DEDMRIYGPL PNRVSRKMSY 420 VEHMKSSKYC ICPMGYEVNS PRIVEAIYYE CVPVIIADNF VPPLNEVLDW SAFSVVVAEK 480 DIPKLKEILL AIPMRKYMRM QTNVKMVQKH FLWNPRPLRY DLFHMILHSI WFSRLNQISL 540 PSAY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-62 | 208 | 492 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 1 | 540 | 1 | 535 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 13 | 537 | 16 | 530 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 1 | 540 | 1 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 159 | 543 | 1 | 386 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 12 | 543 | 1 | 528 | catalytic, putative [Ricinus communis] |