| Basic Information | |
|---|---|
| Species | Eucalyptus grandis |
| Cazyme ID | Eucgr.E00525.1 |
| Family | AA3 |
| Protein Properties | Length: 580 Molecular Weight: 62549.9 Isoelectric Point: 7.2693 |
| Chromosome | Chromosome/Scaffold: 5 Start: 4972118 End: 4976049 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 48 | 573 | 0 |
| YYDYIVIGGGTAGCPLAATLSHNASVLLLERGSSPYGNRNITDLDAFGAALSDLSPSSPSQRFISEDGVINARARVLGGGSCLNAGFYSRAAPQYVRDVG WDGKLVNESYAWVERLVAFEAKIGQWQTAVRDGLLESGVVPDNGFTYDHIPGTKVGGTIFDESGHRHTAADLLEYADPKGIAVLLHASVHKILFKRKGTS RPVAHGVVFRDSTGAKHRAYLRRGPRNEIIVSSGALGSPQLLMLSGLGPKAHLQAHNISLVLDQPMVGQGMSDNPMNAVFIPSPNPVEVSLIQVVGITPF GSFIEAASGENFAGGASTKDYGMFSPKIGQLATLPPRQRTPEALAKAIEDMDRLEQAALQGGFILEKITGPKSTGHMELRSRNPNDNPSVTFNYFQDPDD LRRCVEGLSTIERVIESKAFADFKYDAMTFASLLNLTASAPVNLLPRHRNTSTSLEQYCRDSVMTIWHYHGGCQVGMVVDRDYRVLGVDALRVIDGSTFN HSPGTNPQATVMMLGRYMGVKILNER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 580 Download |
| MVLASWRFLA AAFAAVLFLH GSRASDEAYP TQSYSFVRNA ISAPPLSYYD YIVIGGGTAG 60 CPLAATLSHN ASVLLLERGS SPYGNRNITD LDAFGAALSD LSPSSPSQRF ISEDGVINAR 120 ARVLGGGSCL NAGFYSRAAP QYVRDVGWDG KLVNESYAWV ERLVAFEAKI GQWQTAVRDG 180 LLESGVVPDN GFTYDHIPGT KVGGTIFDES GHRHTAADLL EYADPKGIAV LLHASVHKIL 240 FKRKGTSRPV AHGVVFRDST GAKHRAYLRR GPRNEIIVSS GALGSPQLLM LSGLGPKAHL 300 QAHNISLVLD QPMVGQGMSD NPMNAVFIPS PNPVEVSLIQ VVGITPFGSF IEAASGENFA 360 GGASTKDYGM FSPKIGQLAT LPPRQRTPEA LAKAIEDMDR LEQAALQGGF ILEKITGPKS 420 TGHMELRSRN PNDNPSVTFN YFQDPDDLRR CVEGLSTIER VIESKAFADF KYDAMTFASL 480 LNLTASAPVN LLPRHRNTST SLEQYCRDSV MTIWHYHGGC QVGMVVDRDY RVLGVDALRV 540 IDGSTFNHSP GTNPQATVMM LGRYMGVKIL NERLASEAS* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03970 | Rv0697 | 3.0e-26 | 50 | 562 | 556 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| pfam05199 | GMC_oxred_C | 5.0e-28 | 418 | 562 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR01810 | betA | 4.0e-32 | 50 | 562 | 563 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 7.0e-41 | 49 | 576 | 585 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 22 | 578 | 568 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI34759.1 | 0 | 20 | 579 | 21 | 577 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001053612.1 | 0 | 10 | 577 | 16 | 584 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002282510.1 | 0 | 37 | 579 | 1 | 543 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298074.1 | 0 | 1 | 577 | 1 | 573 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509694.1 | 0 | 6 | 579 | 9 | 547 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 35 | 577 | 13 | 521 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
| PDB | 3gdp_A | 0 | 35 | 577 | 13 | 521 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
| PDB | 3gdn_B | 0 | 35 | 577 | 13 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 35 | 577 | 13 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 35 | 577 | 13 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
