| Basic Information | |
|---|---|
| Species | Eucalyptus grandis |
| Cazyme ID | Eucgr.E02380.1 |
| Family | GT47 |
| Protein Properties | Length: 460 Molecular Weight: 52680.5 Isoelectric Point: 9.5563 |
| Chromosome | Chromosome/Scaffold: 5 Start: 36133183 End: 36138375 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 88 | 382 | 0 |
| LRIYVYEEDEVDGLKALLSGRDGRISPESCVKGQWGSQVKIHKLFLESRFRTRKKEEADLFFVPAYVKCVRMMGGLNDKEINRTYVKVLSQMPYFRLSGG RNHIFVFPSGAGAHLFQSWATYINRSIILTPEGDRTDKRDSSAFNTWKDIIIPGNVDDKMTSNAVVQPLPLRKRKYLANYLGRAQNKVGRLRLIELAKQF PEKLECPELKFKGPDKLGRQEYFEHLRDAKFCLAPRGESSWTLRFYEAFFVECVPVLLSDQAELPFQNVIDYKKISIKWPSSRIGPELLEYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 460 Download |
| MNKPRALGPP QHHHLRSTPC TRTHQIGALL LVVATFFLTR LFDHSFAPCS TATAAIGRDG 60 AHESAVARFD GGGAFAWPRR GYGDRLSLRI YVYEEDEVDG LKALLSGRDG RISPESCVKG 120 QWGSQVKIHK LFLESRFRTR KKEEADLFFV PAYVKCVRMM GGLNDKEINR TYVKVLSQMP 180 YFRLSGGRNH IFVFPSGAGA HLFQSWATYI NRSIILTPEG DRTDKRDSSA FNTWKDIIIP 240 GNVDDKMTSN AVVQPLPLRK RKYLANYLGR AQNKVGRLRL IELAKQFPEK LECPELKFKG 300 PDKLGRQEYF EHLRDAKFCL APRGESSWTL RFYEAFFVEC VPVLLSDQAE LPFQNVIDYK 360 KISIKWPSSR IGPELLEYLE SIPDQSIEEM IANGRQVRCL WVYDPESNPC SATNAILWEL 420 QRKVRYFHQS TETFWLHNGS FVNRDLVEFS KWRPPMPLP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-44 | 88 | 382 | 309 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 2 | 459 | 7 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 2 | 459 | 6 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 2 | 459 | 6 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 13 | 459 | 15 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 20 | 459 | 21 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| FY793498 | 260 | 1 | 258 | 0 |
| CX668832 | 291 | 148 | 436 | 0 |
| FE707914 | 278 | 128 | 403 | 0 |
| ES595772 | 265 | 1 | 262 | 0 |
| FY793499 | 239 | 222 | 460 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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