Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.F02636.1 |
Family | GT47 |
Protein Properties | Length: 495 Molecular Weight: 55269.1 Isoelectric Point: 7.9319 |
Chromosome | Chromosome/Scaffold: 6 Start: 35955639 End: 35958443 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 71 | 418 | 0 |
DRIRVHVAELPRSLNYGLLERYWSSPHPDSRIPADPDHPSRPTHLRKPADYPPYPENPLIKQYSAEYWILGDLETPPGARGGSFAERVASWEEADVVFVP FFATLSAEMQLGRDKGKFRRKEGNEDYARQREAVDLVKGSEAWRRSGGRDHVFVLTDPVAMWHVRDEIAPAILLVVDFGGWYRLDSKSSNGSSSDMVHHT QVSLLKDVVVPYTHLLPRLHLLENQKRQTLLYFKGAKHRHRGGVVREKLWDLLVEVPGVIMEEGFPNATGREQSIKGMSSSEFCLHPAGDTPTSCRLFDA IQSLCIPVIISDDIELPFEGILDYSDFSVFVATADALRPNWLIDRLRS |
Full Sequence |
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Protein Sequence Length: 495 Download |
MPLKNTATAG AGGILHPSTL RPLCSVPSLL LSLALATVLL SSLFFLRSAP PLLRSSSSSS 60 SSEIPPSPSA DRIRVHVAEL PRSLNYGLLE RYWSSPHPDS RIPADPDHPS RPTHLRKPAD 120 YPPYPENPLI KQYSAEYWIL GDLETPPGAR GGSFAERVAS WEEADVVFVP FFATLSAEMQ 180 LGRDKGKFRR KEGNEDYARQ REAVDLVKGS EAWRRSGGRD HVFVLTDPVA MWHVRDEIAP 240 AILLVVDFGG WYRLDSKSSN GSSSDMVHHT QVSLLKDVVV PYTHLLPRLH LLENQKRQTL 300 LYFKGAKHRH RGGVVREKLW DLLVEVPGVI MEEGFPNATG REQSIKGMSS SEFCLHPAGD 360 TPTSCRLFDA IQSLCIPVII SDDIELPFEG ILDYSDFSVF VATADALRPN WLIDRLRSFS 420 EEQKDRFRQN MAKVQPNFEY DSGHQGGIGP IPPDGAVNYI WKKVYQKLPM IKEAIVRERR 480 KPPGVSIPLR CHCT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-61 | 107 | 419 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 73 | 493 | 57 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 1 | 494 | 1 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 24 | 494 | 13 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 73 | 494 | 29 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 68 | 494 | 50 | 478 | catalytic, putative [Ricinus communis] |