y
Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.H02436.1 |
Family | GT47 |
Protein Properties | Length: 434 Molecular Weight: 48589.4 Isoelectric Point: 8.6876 |
Chromosome | Chromosome/Scaffold: 8 Start: 33283453 End: 33290152 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 110 | 386 | 0 |
RDFGVFIYPDGDPNTFYQTPRKLTGKYASEGYFFQNIREGRFRTDDPDRAHLFFIPISCHKMRGKGTSYENMTVIVQNYVDSLIAKYPYWNRTLGADHFF VTCHDVGVRATEGVPLLVKNSIRVVCSPSYDVGFIPHKDVALPQVLQPFALPAGGNDVENRTRLGFWAGHRNSKIRVILARVWENDTELDISNNRISRAT GHLVYQKRFYRTKFCICPGGSQVNSARIADAIHYGCVPVILSNYYDLPFNDILDWRKFSVIVKESEVYNLKQILKNI |
Full Sequence |
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Protein Sequence Length: 434 Download |
MSAGGKQPQP PPPQSPSPSS LFTLRGSLLT LALLTLASFT VVSLNSLRSP AAAAAAPGTL 60 TPSFSILKMS REAAGDGDGD GGGGGGGGEE LSDIYHLPEV FRLNYAAMER DFGVFIYPDG 120 DPNTFYQTPR KLTGKYASEG YFFQNIREGR FRTDDPDRAH LFFIPISCHK MRGKGTSYEN 180 MTVIVQNYVD SLIAKYPYWN RTLGADHFFV TCHDVGVRAT EGVPLLVKNS IRVVCSPSYD 240 VGFIPHKDVA LPQVLQPFAL PAGGNDVENR TRLGFWAGHR NSKIRVILAR VWENDTELDI 300 SNNRISRATG HLVYQKRFYR TKFCICPGGS QVNSARIADA IHYGCVPVIL SNYYDLPFND 360 ILDWRKFSVI VKESEVYNLK QILKNISDAE FLQLHENLVK VQKHFQWNSP PIKYDAFHMV 420 MYELWLRHHV IKY* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-55 | 108 | 386 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 21 | 433 | 8 | 409 | unknown [Glycine max] |
RefSeq | NP_195517.1 | 0 | 19 | 433 | 17 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 12 | 433 | 7 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268836.1 | 0 | 23 | 433 | 14 | 417 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 21 | 433 | 1 | 406 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EH770778 | 275 | 124 | 398 | 0 |
JG847451 | 267 | 91 | 357 | 0 |
GO268625 | 269 | 108 | 376 | 0 |
EG459159 | 264 | 171 | 434 | 0 |
EX317869 | 278 | 133 | 410 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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