Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.I02739.1 |
Family | GT24 |
Protein Properties | Length: 1638 Molecular Weight: 184996 Isoelectric Point: 5.4739 |
Chromosome | Chromosome/Scaffold: 9 Start: 38404399 End: 38422072 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1329 | 1576 | 0 |
INIFSIASGHLYERFLKIMILSVLKNTQRPVKFWFIKNYLSPQFKDVIPHMAHQYGFDYELITYKWPTWLHKQKEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQVVRADMGELYDMDLKGRPLAYTPFCDNNKEMDGYRFWRQGFWKEHLRGRPYHISALYVVDLVKFRETAAGDNLRVFYESLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGTATKSKAKTIDLCNNPMTKEPKL |
Full Sequence |
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Protein Sequence Length: 1638 Download |
MKACCRSGFW IVVVLAVCLG VASVHGENRR PKNVQVALRA KWSGTPLLLE AGELLSKEWK 60 DLFWEFIEVW LHSEGNDAKP STARDCLKII LGHGNSLIGH SLAPLFEFSL LLRSASPRLV 120 LYRQLAEESL SSFPLADDFS SSNVNPGFPS ETEELKRKLD SLPVGGNPDS PNGRCCWVDT 180 GGELFFDIAE LNLWLQNPER SGDVFHQPEL FDFDHVYLDS SIESPIAILY GALGSNCFKE 240 FHGTLVEAAK KGKVIYVVRP VLPSGCESKV GVCGALGTED YVNLGGYGVE LALKNMEYKA 300 MDDSAVKKGV TLEDPRTEDL TQDVRGFIFS KILERKPELT SEIMAFRDYL LSATVSDSLD 360 VWELKDLGHQ TAQRIVHASD PLQSMLEINQ NFPSVVSSLS RMKLNDSVKE EILANQRMIP 420 PGKSLVALNG ALINIEDVDL FLLMDLVHQE MSLADQFAKM KIPQSAIVKL LRTLPPPESS 480 MFRIDFRSSH VHYLNNLEED PMYRRWRSNL NEILMPVFPG QLRYIRKNLY HAVYVIDPGS 540 VCGLESIDMV ISLYENNFPV RFGVILYSSN FIEKSEINGV SRHAEDNGGQ TEDLSSLIIG 600 LFFHVKENHG THLAFQFLSS INRVRSESVD SEDDTLERHH VEAAFVDTLL PKAKSPPQDI 660 LLKLEKDHSV QLLSEESSLF VFKLGLHKRG CCLLMNGLVL DANEEALMNA MNDELPKIQE 720 QVYFGHINSH TDVLDKFLSE SGVSRYNPLI IADSKARPRF VSLSSLVLQG KSVLNEINYL 780 HSPETMDDLK PVSHLLAIDV TSEKGMKLLR EGIRYLMGGS KIARLGVLFN ANQSADSSSL 840 LFMRVFEFTL SSYSHKERVL YFLDQLSLFY ENKYILVSSL ATETTQEFKD KVYELADENG 900 LSSDAFKSML LEFSVNKMRG DLNKVAQCLY KLLGSGSNVN AVITNGRVLF PIEDTFLSDD 960 LRLLESLEFK QRIKYIKEII EEVEWQDIDP DLLTSKFFSD VIMFASSAMA VRERSSESAR 1020 FEVLNAQNSA VLLGNANASV HVDAVVDPLS SSGQKLASLL RILSKYVQPS MRIVLNPLSS 1080 LVDLPLKNYY RYVVPTMEDY STIDYSINGP RAFFANMPLS KTLTMNLDVP EPWLVEPVIA 1140 IHDLDNILLE NLGETRTLQA VFELEALVLT GHCSEKDHEP PRGLQLILGT KSKPHLVDTL 1200 VMANLGYWQM KVSPGVWYLQ LAPGRSSEIY ILKEDGEGSQ NEPSLKRIMI NDLRGKVVHL 1260 EVVKKKGREG EKLLVSSDDE QQSQEKRGAQ NWNSNILKWA SSILGGSEES RSRSAAQEHG 1320 KGGRHGKPIN IFSIASGHLY ERFLKIMILS VLKNTQRPVK FWFIKNYLSP QFKDVIPHMA 1380 HQYGFDYELI TYKWPTWLHK QKEKQRIIWA YKILFLDVIF PLSLEKVIFV DADQVVRADM 1440 GELYDMDLKG RPLAYTPFCD NNKEMDGYRF WRQGFWKEHL RGRPYHISAL YVVDLVKFRE 1500 TAAGDNLRVF YESLSKDPNS LSNLDQDLPN YAQHTVPIFS LPQEWLWCES WCGTATKSKA 1560 KTIDLCNNPM TKEPKLQGAK RIVSEWPDLD LEARTFTAKI LRDEFELQEA VASDKSQGSQ 1620 SDESSVEELD LESKSEL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01501 | Glyco_transf_8 | 5.0e-5 | 1333 | 1528 | 206 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd04194 | GT8_A4GalT_like | 2.0e-14 | 1329 | 1545 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd00505 | Glyco_transf_8 | 2.0e-57 | 1329 | 1576 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam06427 | UDP-g_GGTase | 6.0e-75 | 999 | 1204 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
cd06432 | GT8_HUGT1_C_like | 8.0e-175 | 1329 | 1576 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG51883.1 | 0 | 6 | 1637 | 8 | 1674 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
DDBJ | BAD28382.1 | 0 | 27 | 1631 | 33 | 1626 | putative UDP-glucose:glycoprotein glucosyltransferase [Oryza sativa Japonica Group] |
RefSeq | NP_177278.3 | 0 | 6 | 1637 | 8 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002268972.1 | 0 | 1 | 1637 | 1 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002529534.1 | 0 | 1 | 1526 | 1 | 1499 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |