Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.J00384.1 |
Family | GT47 |
Protein Properties | Length: 494 Molecular Weight: 53720 Isoelectric Point: 11.6066 |
Chromosome | Chromosome/Scaffold: 10 Start: 3761645 End: 3764541 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 113 | 239 | 8.3e-35 |
RGLKIYVYDLPPKYNSEWLSNERCRTHLFASEVAIHRALLTSDVRTLDPHEADFFFVPVYVSCNFSTTNGFPAIGHARSLLLSAVQLISSEQPFWNRSSG SDHVFVASHDYGACFHAMVRSSCRRWG |
Full Sequence |
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Protein Sequence Length: 494 Download |
MAELKRAPPT SKSRGFYVRM RLLHGYGKHH QRLAQDKKSF FHRYYKWVLW LSLSFYFFCP 60 YLLSHSPKQR LNPLRTGSAG STHSSRALFE SSLSLSNSSS TRSQEPEIDQ ELRGLKIYVY 120 DLPPKYNSEW LSNERCRTHL FASEVAIHRA LLTSDVRTLD PHEADFFFVP VYVSCNFSTT 180 NGFPAIGHAR SLLLSAVQLI SSEQPFWNRS SGSDHVFVAS HDYGACFHAM VRSSCRRWGA 240 GIFEEVHHTA DVRGQLRPPV SGRRARGDPA LHSAGKFTED AGVVAGEQRP PRHLGLLQGQ 300 DGSPPQEHQR ALLQQGGAIG DLAQVQRRLA VLPPAAQVRR LPVGDRPVRV LPLPARVGPV 360 EPAPGGVRGP GLRPRRHRRR HPPPLPGGRA VAGNIARGGG AGRRAARPDP GPRGGDQPER 420 HPAEPLAAGG PAGPAVPRPG RARRRHVARA AGPGGEAGPL VQEEQGLRPM RARGARGGGP 480 PGVGIGWLLM GAS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-28 | 113 | 235 | 126 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33322.1 | 0 | 20 | 230 | 1 | 204 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
GenBank | ABI64067.1 | 0 | 20 | 230 | 1 | 204 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
RefSeq | XP_002275679.1 | 0 | 11 | 230 | 8 | 214 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002314302.1 | 0 | 1 | 230 | 2 | 224 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523710.1 | 0 | 1 | 230 | 1 | 223 | transferase, putative [Ricinus communis] |