| Basic Information | |
|---|---|
| Species | Eucalyptus grandis |
| Cazyme ID | Eucgr.J02121.1 |
| Family | GT47 |
| Protein Properties | Length: 322 Molecular Weight: 35365.6 Isoelectric Point: 7.2682 |
| Chromosome | Chromosome/Scaffold: 10 Start: 27200106 End: 27201199 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 32 | 255 | 8.8e-39 |
| AESLFLASLLGSPFVTENPSEAHLFFVPFDGGLSERSVARVVRDLRADHPYWNRTLGADHFYASCDGIGFGSDRNLLELKKNAVQLSCFPASGGRFVPHK DVALPPAAVAPAGDGGPRAPPPNGTAEHLAYARLGAIKDPGLTDRLAGDRDFLIESEPSDRATIERRLAASEFCLFDLGGDVSWIGDAMRFGCVPVVITD RSIQDLPLIDVLRWQEMAVFVGSA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 322 Download |
| MPVAHPSFLP LLLLLPLLPL LAPPTFKFKS EAESLFLASL LGSPFVTENP SEAHLFFVPF 60 DGGLSERSVA RVVRDLRADH PYWNRTLGAD HFYASCDGIG FGSDRNLLEL KKNAVQLSCF 120 PASGGRFVPH KDVALPPAAV APAGDGGPRA PPPNGTAEHL AYARLGAIKD PGLTDRLAGD 180 RDFLIESEPS DRATIERRLA ASEFCLFDLG GDVSWIGDAM RFGCVPVVIT DRSIQDLPLI 240 DVLRWQEMAV FVGSAGGAEA VKRALTGLTR ERLERMRESC VAASRHFAWN RPPQPLDAFH 300 MVVYQLWLRR HTIRYARRDF S* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-25 | 44 | 252 | 234 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002282317.1 | 0 | 28 | 320 | 65 | 359 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002309859.1 | 0 | 27 | 315 | 107 | 420 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002311191.1 | 0 | 26 | 320 | 55 | 344 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002316258.1 | 0 | 3 | 320 | 32 | 338 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524235.1 | 0 | 6 | 320 | 37 | 336 | conserved hypothetical protein [Ricinus communis] |
