| Basic Information | |
|---|---|
| Species | Eucalyptus grandis |
| Cazyme ID | Eucgr.K01713.1 |
| Family | CE1 |
| Protein Properties | Length: 254 Molecular Weight: 28468.2 Isoelectric Point: 6.3388 |
| Chromosome | Chromosome/Scaffold: 11 Start: 20788891 End: 20793108 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 13 | 135 | 1.3e-23 |
| SPTLGCSMNFHIYFPPSPPSSPSPKFPVLYWLSGLTCTDENFIVKSGAQRAASKEGIALIAPDTSPRGLNVEGEAESWDFGVGAGFYLNATQEKWKNWRM YDYIVKELPNLLAENFPQLDTAR | |||
| Full Sequence |
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| Protein Sequence Length: 254 Download |
| MFGGYNRRYK HFSPTLGCSM NFHIYFPPSP PSSPSPKFPV LYWLSGLTCT DENFIVKSGA 60 QRAASKEGIA LIAPDTSPRG LNVEGEAESW DFGVGAGFYL NATQEKWKNW RMYDYIVKEL 120 PNLLAENFPQ LDTARHLYLS VSAFAPIGNP VNCPWGQKAF TNYLGGNKAD WEEYDATCLV 180 AKFHDVSATI LIDQGEDDKF LHNQLLPDKF SEACKKHGVP VLVRLQPGYD HSFFFIATFI 240 DDHILHHAQA LNL* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01738 | DLH | 0.005 | 185 | 234 | 50 | + Dienelactone hydrolase family. | ||
| pfam00756 | Esterase | 2.0e-35 | 13 | 246 | 266 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 5.0e-59 | 1 | 253 | 301 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 2.0e-110 | 2 | 251 | 272 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 9.0e-174 | 1 | 253 | 274 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ11734.1 | 0 | 1 | 253 | 13 | 284 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| GenBank | ACJ84789.1 | 0 | 1 | 253 | 14 | 284 | unknown [Medicago truncatula] |
| GenBank | ACU19052.1 | 0 | 1 | 253 | 13 | 284 | unknown [Glycine max] |
| RefSeq | XP_002284489.1 | 0 | 1 | 253 | 13 | 284 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002308013.1 | 0 | 1 | 239 | 13 | 270 | esterase d, s-formylglutathione hydrolase [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 2 | 252 | 12 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 2 | 252 | 12 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 2 | 252 | 13 | 279 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 2 | 252 | 13 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 2 | 252 | 13 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| FY793751 | 267 | 1 | 246 | 0 |
| JG618514 | 274 | 1 | 253 | 0 |
| DV157903 | 275 | 1 | 254 | 0 |
| EC982699 | 274 | 1 | 253 | 0 |
| DT549152 | 272 | 1 | 251 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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