| Basic Information | |
|---|---|
| Species | Eucalyptus grandis |
| Cazyme ID | Eucgr.K02114.1 |
| Family | AA3 |
| Protein Properties | Length: 749 Molecular Weight: 81530.7 Isoelectric Point: 7.7368 |
| Chromosome | Chromosome/Scaffold: 11 Start: 28230329 End: 28237181 |
| Description | Long-chain fatty alcohol dehydrogenase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA3 | 224 | 742 | 4.2039e-45 |
| VTQIPQHNAFKIKCDVVIIGSGCGGGVAAAVLAHSGQKVVVLEKGNYFVPQDYSSLEGPSLDQLYESSALLSTVDGKIVVLAGSTVGGGSAVNWSACIRT PSHVLKEWSVDHKIRLFGTPDYGSAMDAVCKKIGVTQKCEQEGFQNQILRKGCESLGLKVEAVARNSSEGHFCGSCCYGCRTGDKKGTDSTWLVDAVENG AVILTGCKAKKLILENTPHGEKPKKCLGVIASSVLNKDVTKELHIEAKVTIAACSAVSTPPLLISSGLKNPNIGRNLHLHPCAFAWGYFPENLTGIQGKV YEGGIITSLNRVVLETGAPVPAIIETPSLGPGLFSALCPWTSGANMKERMRKYSRTAHLFTLVRDKGSGEVREEGKIVYNLSEFDKEHMKIGLRQALRIL IAAGAEEVGTHRSDGQRMKCQGTKEEDIEEFLNDIVISGGPTSREELWNLYCCAHPMGSCRIGASERDGAVDESGESWEAKGLFVCDGSLMPTAIGVNPM ITIESTAYCIAKKIAESLS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 749 Download |
| MAGECHPLLR GGRRESRYGH GFSPAQIQAL AAICETLIPS VSLDSINPKI PHDDPALHGF 60 YSASGSQPSV PDEVAEILTK RAQRQVVVMV SIVLKMLSFR LGTLVLCWGS CLASTWPFIL 120 NFSEMPVERR ERVLMNWSRQ KFVVPLRVVF MMIKIYCLFI FYTRTDENSN NLAWEAIGYR 180 VDKRQKPNES HNKQERPLQR GLVETVHETD SSLIQSLTQK GLKVTQIPQH NAFKIKCDVV 240 IIGSGCGGGV AAAVLAHSGQ KVVVLEKGNY FVPQDYSSLE GPSLDQLYES SALLSTVDGK 300 IVVLAGSTVG GGSAVNWSAC IRTPSHVLKE WSVDHKIRLF GTPDYGSAMD AVCKKIGVTQ 360 KCEQEGFQNQ ILRKGCESLG LKVEAVARNS SEGHFCGSCC YGCRTGDKKG TDSTWLVDAV 420 ENGAVILTGC KAKKLILENT PHGEKPKKCL GVIASSVLNK DVTKELHIEA KVTIAACSAV 480 STPPLLISSG LKNPNIGRNL HLHPCAFAWG YFPENLTGIQ GKVYEGGIIT SLNRVVLETG 540 APVPAIIETP SLGPGLFSAL CPWTSGANMK ERMRKYSRTA HLFTLVRDKG SGEVREEGKI 600 VYNLSEFDKE HMKIGLRQAL RILIAAGAEE VGTHRSDGQR MKCQGTKEED IEEFLNDIVI 660 SGGPTSREEL WNLYCCAHPM GSCRIGASER DGAVDESGES WEAKGLFVCD GSLMPTAIGV 720 NPMITIESTA YCIAKKIAES LSSKQEDL* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01810 | betA | 0.009 | 642 | 745 | 105 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| PRK02106 | PRK02106 | 0.008 | 678 | 738 | 61 | + choline dehydrogenase; Validated | ||
| pfam05199 | GMC_oxred_C | 5.0e-21 | 602 | 733 | 132 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| COG2303 | BetA | 7.0e-25 | 261 | 739 | 547 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| pfam00732 | GMC_oxred_N | 4.0e-87 | 285 | 505 | 224 | + GMC oxidoreductase. This family of proteins bind FAD as a cofactor. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACF22878.1 | 0 | 18 | 741 | 1 | 716 | alcohol oxidase [Glycine max] |
| EMBL | CAN71289.1 | 0 | 1 | 746 | 1 | 740 | hypothetical protein [Vitis vinifera] |
| EMBL | CAP15763.1 | 0 | 4 | 745 | 8 | 750 | long chain fatty alcohol oxidase FAO2 [Lotus japonicus] |
| RefSeq | XP_002285334.1 | 0 | 1 | 746 | 1 | 740 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002529832.1 | 0 | 5 | 741 | 7 | 741 | electron carrier, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3t37_A | 0.000000002 | 236 | 716 | 17 | 499 | A Chain A, Crystal Structure Of Pyridoxine 4-Oxidase From Mesorbium Loti |
| PDB | 2gew_A | 0.000006 | 676 | 730 | 440 | 489 | A Chain A, Crystal Structure Of Pyridoxine 4-Oxidase From Mesorbium Loti |
| PDB | 1n4w_A | 0.000006 | 676 | 730 | 440 | 489 | A Chain A, Crystal Structure Of Pyridoxine 4-Oxidase From Mesorbium Loti |
| PDB | 1n4v_A | 0.000006 | 676 | 730 | 440 | 489 | A Chain A, Crystal Structure Of Pyridoxine 4-Oxidase From Mesorbium Loti |
| PDB | 1n4u_A | 0.000006 | 676 | 730 | 440 | 489 | A Chain A, Crystal Structure Of Pyridoxine 4-Oxidase From Mesorbium Loti |
