| Basic Information | |
|---|---|
| Species | Eucalyptus grandis |
| Cazyme ID | Eucgr.K02568.1 |
| Family | GT41 |
| Protein Properties | Length: 921 Molecular Weight: 101797 Isoelectric Point: 5.7824 |
| Chromosome | Chromosome/Scaffold: 11 Start: 33143330 End: 33160583 |
| Description | Tetratricopeptide repeat (TPR)-like superfamily protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT41 | 364 | 852 | 0 |
| PNFSQSLNNLGVVYTVQGKMDAAASMIEKAIIANPTYAEAYNNLGVLYRDAGNITMAINAYEQCLKIDPDSRNAGQNRLLAMNYINEGHDDKLFEAHRDW GRRFMRLFPQYTSWENTKDPDRPLVIGYVSPDYFTHSVSYFIEAPLSCHNYSNYNVAVYSAVVKADAKTFRFRDKVLKNGGIWRDIYGVDEKKVASMIRE DKVDILVELTGHTANNKLGMMACRPAPVQVTWIGYPNTTGLPTIDYRITDSLADPPDTKQKHVEELIRLPECFLCYTPSPEAGPVCPTPALSNGFVTFGS FNNLAKITPKVLQVWARILCAVPNSRLVVKCKPFCCDSVRQRFLATLEQLGLESLRVDLLPLILLNHDHMQAYSLMDISLDTFPYAGTTTTCESLYMGVP CIAMAGSVHAHNVGVSLLTKVGLGHLIAKNEDEYVESALQLASDVNALSKLRMSLRELMSKSPVCDGPKFITGLESTYRSMWRRYCKGD | |||
| Full Sequence |
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| Protein Sequence Length: 921 Download |
| MAWTEKDAVS EGGKDLIAEN GFLKASGSSP ATDTTVSGAS LKKAFEGKDA LSYANILRSR 60 NKFADALALY EGILEKDSAM VEAYIGKGIC LQMQNMGRLA FDSFAEAIRL DPQNACALTH 120 CGILYKDEGR LMEAAESYQK ALKADPLYKP AAECLAIVLT DIGTSLKLGG NTQEGIQKYY 180 EALKIDPHYA PAYYNLGVVY SEMMQYDTAL NCYEKAALER PLYAEAYCNM GVIYKNRGDL 240 ESAIACYERC LAVSPNFEIA KNNMAIALTD LGTKVKLEGD INQGVAYYKK ALYYNWHYAD 300 AMYNLGVAYG EMLKFDMAIV FYELAFHFNP HCAEACNNLG VIYKDRDNLD KAVECYQLAL 360 SIKPNFSQSL NNLGVVYTVQ GKMDAAASMI EKAIIANPTY AEAYNNLGVL YRDAGNITMA 420 INAYEQCLKI DPDSRNAGQN RLLAMNYINE GHDDKLFEAH RDWGRRFMRL FPQYTSWENT 480 KDPDRPLVIG YVSPDYFTHS VSYFIEAPLS CHNYSNYNVA VYSAVVKADA KTFRFRDKVL 540 KNGGIWRDIY GVDEKKVASM IREDKVDILV ELTGHTANNK LGMMACRPAP VQVTWIGYPN 600 TTGLPTIDYR ITDSLADPPD TKQKHVEELI RLPECFLCYT PSPEAGPVCP TPALSNGFVT 660 FGSFNNLAKI TPKVLQVWAR ILCAVPNSRL VVKCKPFCCD SVRQRFLATL EQLGLESLRV 720 DLLPLILLNH DHMQAYSLMD ISLDTFPYAG TTTTCESLYM GVPCIAMAGS VHAHNVGVSL 780 LTKVGLGHLI AKNEDEYVES ALQLASDVNA LSKLRMSLRE LMSKSPVCDG PKFITGLEST 840 YRSMWRRYCK GDVPALRNLE MLQQHAASEP LSMPAASISV SPEIPSESAK ANGFAQVAPV 900 LTLTSSEENG QVNEAAKDGK * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam13844 | Glyco_transf_41 | 7.0e-20 | 487 | 636 | 151 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
| cd00189 | TPR | 4.0e-21 | 334 | 433 | 100 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| pfam13844 | Glyco_transf_41 | 2.0e-22 | 659 | 845 | 187 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
| COG3914 | Spy | 6.0e-92 | 316 | 848 | 562 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005515 | protein binding |
| GO:0042802 | identical protein binding |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| Swiss-Prot | O82039 | 0 | 1 | 920 | 1 | 930 | SPY_PETHY RecName: Full=Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY; AltName: Full=PhSPY |
| RefSeq | XP_002281883.1 | 0 | 1 | 910 | 1 | 912 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002308458.1 | 0 | 1 | 920 | 1 | 932 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002323412.1 | 0 | 1 | 898 | 1 | 906 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530535.1 | 0 | 1 | 909 | 1 | 914 | o-linked n-acetylglucosamine transferase, ogt, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1w3b_B | 3e-35 | 107 | 408 | 59 | 380 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 9e-32 | 109 | 440 | 27 | 344 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 2e-26 | 55 | 374 | 75 | 380 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 1e-17 | 55 | 312 | 143 | 386 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 0.0000000002 | 51 | 239 | 207 | 388 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DY295408 | 401 | 429 | 826 | 0 |
| HO781209 | 361 | 492 | 852 | 0 |
| HO781209 | 120 | 392 | 511 | 0 |
| HO781209 | 67 | 213 | 277 | 0.0003 |
| HO781209 | 58 | 329 | 384 | 4.8 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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