| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G000976_T02 |
| Family | GT47 |
| Protein Properties | Length: 268 Molecular Weight: 31022.8 Isoelectric Point: 8.3525 |
| Chromosome | Chromosome/Scaffold: 4 Start: 234623498 End: 234626076 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 10 | 220 | 0 |
| TSYENMTVIVKDYVEGLINKYPYWNRTLGADHFFVTCHDVGVRAFEGLKFMVKNSIRVVCSPSYNVDFIPHKDIALPQVLQPFALHEGGNDIDNRVILGF WAGHRNSKIRVILARVWENDTELAISNNRISRAIGELVYQKQFYRTKFCICPGGSQVNSARISDSIHYGCVPVILSDYYDLPFNDALDWRKFAVILRERD VYQLKNILKSI | |||
| Full Sequence |
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| Protein Sequence Length: 268 Download |
| MCVVLTLQGT SYENMTVIVK DYVEGLINKY PYWNRTLGAD HFFVTCHDVG VRAFEGLKFM 60 VKNSIRVVCS PSYNVDFIPH KDIALPQVLQ PFALHEGGND IDNRVILGFW AGHRNSKIRV 120 ILARVWENDT ELAISNNRIS RAIGELVYQK QFYRTKFCIC PGGSQVNSAR ISDSIHYGCV 180 PVILSDYYDL PFNDALDWRK FAVILRERDV YQLKNILKSI SQEEFISLHK SLVQVQKHFV 240 WHSPPVSYDA FHMVMYELWL RHNVIKY* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-45 | 18 | 220 | 216 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG33948.1 | 0 | 8 | 267 | 144 | 403 | exostosin-like [Zea mays] |
| RefSeq | NP_001046127.1 | 0 | 8 | 267 | 143 | 402 | Os02g0187200 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001132213.1 | 0 | 8 | 267 | 144 | 403 | hypothetical protein LOC100193644 [Zea mays] |
| RefSeq | NP_001147269.1 | 0 | 8 | 267 | 144 | 403 | exostosin-like [Zea mays] |
| RefSeq | XP_002453426.1 | 0 | 8 | 267 | 144 | 403 | hypothetical protein SORBIDRAFT_04g005890 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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