y
Basic Information | |
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Species | Zea mays |
Cazyme ID | GRMZM2G001938_T01 |
Family | GT47 |
Protein Properties | Length: 577 Molecular Weight: 63501.2 Isoelectric Point: 9.1169 |
Chromosome | Chromosome/Scaffold: 7 Start: 13841282 End: 13843453 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 231 | 527 | 0 |
ERQLKVYVYEEGEPPVFHDGPCRSIYSTEGRFIHSMETETEAEEGRRLRTRDPARAHVFFLPFSVVKMVQTIYEPGSRDMAPLKRTVADYVRVLSSKYPY WNRSLGADHFMLSCHDWGPYVSSANAQLFGNSIRVLCNANTSEGFDPARDVSLPQVNLRSDAVERQVGGPSASRRPVLAFFAGGNHGPVRPALLAHWGPG GRRGGDPDVRVSEYLPRGGGAPSYADMMRRSRFCLCPGGYEVASPRLAEALYLGCVPVVVDDGEYALPFADVLDWDAFALRLRVADIPRLKEILAAV |
Full Sequence |
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Protein Sequence Length: 577 Download |
MPASAATTTT TSSAAPSPSL LPCLHVHAHG RASAAAACCL LVLVTFLVVA ACWWDPRTRE 60 ASSWFLSPPR SAPSSFSSLT SAGGVGGGGE HLLATASSYY SAAAGFRNST GKEVHQEVRG 120 HGGDDRGFLS FVNSSFGYDE APPPSAPAPA SPVTGGSDEV IIQSTPPQVE RRRDDVKLER 180 LELGLARARS AIMEAIRKKD KVSPLPDKDY VPMGPVYRNA HVFHRSYLEM ERQLKVYVYE 240 EGEPPVFHDG PCRSIYSTEG RFIHSMETET EAEEGRRLRT RDPARAHVFF LPFSVVKMVQ 300 TIYEPGSRDM APLKRTVADY VRVLSSKYPY WNRSLGADHF MLSCHDWGPY VSSANAQLFG 360 NSIRVLCNAN TSEGFDPARD VSLPQVNLRS DAVERQVGGP SASRRPVLAF FAGGNHGPVR 420 PALLAHWGPG GRRGGDPDVR VSEYLPRGGG APSYADMMRR SRFCLCPGGY EVASPRLAEA 480 LYLGCVPVVV DDGEYALPFA DVLDWDAFAL RLRVADIPRL KEILAAVSPR QYIRMQRRVR 540 MVRRHFMLHG GPPRRYDAFH MILHSVWLRR LNVRIAA 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-55 | 230 | 527 | 316 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 170 | 575 | 20 | 405 | unnamed protein product [Arabidopsis thaliana] |
GenBank | EAZ03045.1 | 0 | 155 | 577 | 190 | 598 | hypothetical protein OsI_25187 [Oryza sativa Indica Group] |
RefSeq | NP_001031828.1 | 0 | 170 | 575 | 130 | 515 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_001059081.1 | 0 | 155 | 577 | 195 | 603 | Os07g0188700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002459470.1 | 0 | 10 | 577 | 4 | 580 | hypothetical protein SORBIDRAFT_02g005180 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |