| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G013255_T02 |
| Family | GH29 |
| Protein Properties | Length: 189 Molecular Weight: 20627.3 Isoelectric Point: 5.9151 |
| Chromosome | Chromosome/Scaffold: 7 Start: 140895637 End: 140896537 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH29 | 41 | 181 | 0 |
| PQLRWQRREVIMFFHFGMNTFTDSEWGTGSEDPSLFRPAGLNATQWMDAARAAGASLVILVAKHHDGFCLWPSDYTAHSVRASPWRGGRGDVVREFVGAA RARGLDAGLYLSPWDRHDQRYGEEVAYNEYYEAQLHELLTG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 189 Download |
| MASPLLCLAA AALAVAVLVS ATEAWRATPP PLPVLPIPSA PQLRWQRREV IMFFHFGMNT 60 FTDSEWGTGS EDPSLFRPAG LNATQWMDAA RAAGASLVIL VAKHHDGFCL WPSDYTAHSV 120 RASPWRGGRG DVVREFVGAA RARGLDAGLY LSPWDRHDQR YGEEVAYNEY YEAQLHELLT 180 GSVPSCCD* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 1.0e-13 | 52 | 180 | 141 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 1.0e-14 | 75 | 180 | 120 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 1.0e-32 | 42 | 181 | 145 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABG73453.1 | 0 | 40 | 181 | 42 | 183 | glycosyl hydrolase family 29 [Oryza brachyantha] |
| GenBank | ACR35251.1 | 0 | 1 | 181 | 1 | 181 | unknown [Zea mays] |
| RefSeq | NP_001063703.1 | 0 | 40 | 181 | 45 | 186 | Os09g0520800 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001151568.1 | 0 | 1 | 181 | 1 | 181 | alpha-L-fucosidase 1 [Zea mays] |
| RefSeq | XP_002462685.1 | 0 | 1 | 181 | 1 | 182 | hypothetical protein SORBIDRAFT_02g030220 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3uet_B | 0 | 38 | 184 | 19 | 165 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
| PDB | 3uet_A | 0 | 38 | 184 | 19 | 165 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
| PDB | 3ues_B | 0 | 38 | 184 | 19 | 165 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 38 | 184 | 19 | 165 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 38 | 184 | 21 | 167 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
