| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G014955_T01 |
| Family | GT65 |
| Protein Properties | Length: 443 Molecular Weight: 50206.7 Isoelectric Point: 8.4581 |
| Chromosome | Chromosome/Scaffold: 1 Start: 278665409 End: 278667871 |
| Description | O-fucosyltransferase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT65 | 78 | 387 | 0 |
| GLNNQKIAFARACLTARFLNRSLLMPSLSASLFYKEVDLLQPINFDKVFDFNKFNARCHGFVRLAQYSEVSNRTEPFKLQKGTGRRWTADRDLDQLQQSI GSNADDSEVIEIVGKNPFLWPDHWPVKDYAKIFDCLVLVPEIETEVVNVISKIREAGQRARHEAGSSHSKQRRDSSTNPPVPYVAVHMRIEKDWMIHCKK WEQRSKSHEICSSKEEIIHKVSQITDLHRPVVVYLAVADSLLEDDSITSGWRVGMVAYEKKKLGVTDVYDRQPYLIKSAIDFEVCSRADVFVGNSFSTFS NLVVLSRTER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 443 Download |
| MNILLELKHL KPFSIPARLV ICKGLLIVIA LILLRAIVSP FLAIDSSEKK EFYESTAPDL 60 LPRIRRDKFL EVPQIIWGLN NQKIAFARAC LTARFLNRSL LMPSLSASLF YKEVDLLQPI 120 NFDKVFDFNK FNARCHGFVR LAQYSEVSNR TEPFKLQKGT GRRWTADRDL DQLQQSIGSN 180 ADDSEVIEIV GKNPFLWPDH WPVKDYAKIF DCLVLVPEIE TEVVNVISKI REAGQRARHE 240 AGSSHSKQRR DSSTNPPVPY VAVHMRIEKD WMIHCKKWEQ RSKSHEICSS KEEIIHKVSQ 300 ITDLHRPVVV YLAVADSLLE DDSITSGWRV GMVAYEKKKL GVTDVYDRQP YLIKSAIDFE 360 VCSRADVFVG NSFSTFSNLV VLSRTERLYN LGKASSCGEN IGLSSYAYNV MGGDGGPQRW 420 MTDMSDGSLQ RLSYGTNNVS CH* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11296 | O-FucT_like | 0.009 | 69 | 103 | 35 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11299 | O-FucT_plant | 0.0002 | 210 | 393 | 204 | + GDP-fucose protein O-fucosyltransferase, plant specific subfamily. Some members of this plant-specific family of O-fucosyltransferases have been annotated as auxin-independent growth promotors. The function of the protein seems unclear. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11302 | O-FucT-1 | 6.0e-5 | 259 | 384 | 146 | + GDP-fucose protein O-fucosyltransferase 1. The protein O-fucosyltransferase 1 (Ofut1 or O-FucT-1) adds O-fucose to EGF (epidermal growth factor-like) repeats. The O-fucsosylation of the Notch receptor signaling protein is dependent on this enzyme, which requires GDP-fucose as a substrate. O-fucose residues added to the target of O-FucT-1 may be further elongated by other glycosyltransferases. On top of O-fucosylation, O-FucT-1 may have other functions such as the regulation of the Notch receptor exit from the ER. Six highly conserved cysteines are present in O-FucT-1, which is a soluble ER protein, as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The membrane-bound pre-protein is released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. O-FucT-1 is similar to family 1 glycosyltransferases (GT1). | ||
| cd11296 | O-FucT_like | 9.0e-24 | 228 | 387 | 164 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| pfam10250 | O-FucT | 1.0e-26 | 78 | 385 | 340 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACN28408.1 | 0 | 1 | 442 | 1 | 442 | unknown [Zea mays] |
| EMBL | CAH40837.1 | 0 | 1 | 442 | 1 | 441 | protein-O-fucosyltransferase 1 [Oryza sativa] |
| EMBL | CAH40838.1 | 0 | 1 | 442 | 1 | 441 | protein-O-fucosyltransferase 1 [Saccharum officinarum] |
| RefSeq | NP_001147772.1 | 0 | 1 | 442 | 1 | 442 | protein-O-fucosyltransferase 1 [Zea mays] |
| RefSeq | XP_002451612.1 | 0 | 1 | 442 | 1 | 442 | hypothetical protein SORBIDRAFT_04g004590 [Sorghum bicolor] |
