| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G023020_T01 |
| Family | GT47 |
| Protein Properties | Length: 428 Molecular Weight: 48107.4 Isoelectric Point: 6.9448 |
| Chromosome | Chromosome/Scaffold: 2 Start: 62924015 End: 62927608 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 60 | 354 | 0 |
| RLKVFIYDLPRKYNKKMVTKDSRCLSHMFAAEIFMHRFLLSSAVRTLNPKEADWFYTPVYTTCDLTNAGLPLPFKSPRVMRSAIQYISNKWPFWNRTDGA DHFFVVPHDFAACFHYQEEKAIERGILPLLRRATLVQTFGQENHVCLKEGSIIIPPYAPPQKMQAHLISPDTPRSIFVYFRGLFYDTGNDPEGGYYARGA RASLWENFKSNPLFDISTDHPATYYEDMQRAVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVEEKDVPKLDTILTS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 428 Download |
| MGSRKGWFPV ALLLLADSAL WPPVAAAAAG GGEAEHAVQQ HSERISGSAG DVLEDNPVGR 60 LKVFIYDLPR KYNKKMVTKD SRCLSHMFAA EIFMHRFLLS SAVRTLNPKE ADWFYTPVYT 120 TCDLTNAGLP LPFKSPRVMR SAIQYISNKW PFWNRTDGAD HFFVVPHDFA ACFHYQEEKA 180 IERGILPLLR RATLVQTFGQ ENHVCLKEGS IIIPPYAPPQ KMQAHLISPD TPRSIFVYFR 240 GLFYDTGNDP EGGYYARGAR ASLWENFKSN PLFDISTDHP ATYYEDMQRA VFCLCPLGWA 300 PWSPRLVEAV VFGCIPVIIA DDIVLPFADA IPWEEIGVFV EEKDVPKLDT ILTSMPIDDI 360 LRKQRLLANP SMKQAMLFPQ PAQPRDAFHQ ILNGLARKLP HPEGTFLQPG DQRLNWTAGP 420 VGDLKPW* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 3.0e-85 | 60 | 355 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACF84255.1 | 0 | 1 | 427 | 1 | 427 | unknown [Zea mays] |
| RefSeq | NP_001052673.1 | 0 | 31 | 427 | 24 | 420 | Os04g0398600 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001149267.1 | 0 | 32 | 427 | 32 | 427 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
| RefSeq | XP_002446363.1 | 0 | 36 | 427 | 39 | 430 | hypothetical protein SORBIDRAFT_06g014730 [Sorghum bicolor] |
| RefSeq | XP_002452172.1 | 0 | 3 | 427 | 4 | 432 | hypothetical protein SORBIDRAFT_04g021180 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
