| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G030713_T01 |
| Family | GT68 |
| Protein Properties | Length: 454 Molecular Weight: 50737.4 Isoelectric Point: 7.4637 |
| Chromosome | Chromosome/Scaffold: 2 Start: 206365031 End: 206369304 |
| Description | O-fucosyltransferase family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT68 | 138 | 430 | 0 |
| LVVPSQKADYQYDRVLDINHINDCIGRKVVITYEEFVEKRKKVAIDQFICYAASPPCFLDEEHIKKLKGLGISLSKIEAAWPEDAKLKEPKKRSVGDIAP KFSTEAEVLAIGDMFYADMEDEWLNQPGGPLAHKCKALIQPSRLIVLTAQRFVQTFLGGNYIALHFRRHGFLKFCNVKKESCFFPIPQAAECILRIVEKA NAPVIYLSTDAAESETNLLQSLVVFNDRQVPLVKRPEHHSSEKWDALLNRNRMGGDGQVDAMLDKTICALSNVFIGSSGSTFTEDIFRLRRGW | |||
| Full Sequence |
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| Protein Sequence Length: 454 Download |
| MREAELHALY LLRSQRSGLL SLFNRTAAPT NGSAPAPISL SDLQSALESQ IKINREIQAA 60 LLSSHRSGSG NATEDGLDLD LPFSGCRKRE LPASRRTIEW NPKKDRFLLV ICISGQMSNH 120 LICLEKHMFM AALLGRTLVV PSQKADYQYD RVLDINHIND CIGRKVVITY EEFVEKRKKV 180 AIDQFICYAA SPPCFLDEEH IKKLKGLGIS LSKIEAAWPE DAKLKEPKKR SVGDIAPKFS 240 TEAEVLAIGD MFYADMEDEW LNQPGGPLAH KCKALIQPSR LIVLTAQRFV QTFLGGNYIA 300 LHFRRHGFLK FCNVKKESCF FPIPQAAECI LRIVEKANAP VIYLSTDAAE SETNLLQSLV 360 VFNDRQVPLV KRPEHHSSEK WDALLNRNRM GGDGQVDAML DKTICALSNV FIGSSGSTFT 420 EDIFRLRRGW GSASHCDEYL CQGELPNFIA ELD* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11296 | O-FucT_like | 2.0e-5 | 107 | 150 | 44 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11548 | NodZ_like | 2.0e-6 | 275 | 421 | 154 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| pfam10250 | O-FucT | 3.0e-9 | 131 | 428 | 343 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| cd11298 | O-FucT-2 | 1.0e-12 | 294 | 427 | 134 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 8.0e-19 | 268 | 428 | 171 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001060060.1 | 0 | 1 | 453 | 102 | 557 | Os07g0572600 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_173170.2 | 0 | 1 | 451 | 106 | 562 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002264087.1 | 0 | 1 | 451 | 88 | 557 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002303337.1 | 0 | 1 | 451 | 70 | 525 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002460894.1 | 0 | 1 | 453 | 110 | 562 | hypothetical protein SORBIDRAFT_02g037060 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4ap6_D | 0.002 | 294 | 420 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
| PDB | 4ap6_C | 0.002 | 294 | 420 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
| PDB | 4ap6_B | 0.002 | 294 | 420 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
| PDB | 4ap6_A | 0.002 | 294 | 420 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
| PDB | 4ap5_B | 0.003 | 294 | 420 | 263 | 369 | A Chain A, Crystal Structure Of Human Pofut2 |
| Hydropathy |
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