| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G046558_T02 |
| Family | CE1 |
| Protein Properties | Length: 291 Molecular Weight: 31886.1 Isoelectric Point: 6.5961 |
| Chromosome | Chromosome/Scaffold: 8 Start: 159254849 End: 159263818 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE1 | 31 | 284 | 0 |
| SATLGCAMTFSIYLPPSPASNLPVLYWLSGLTCTDENFIIKSGAQRAAAAHGIALVAPDTSPRGLNIEGESDSYDFGVGAGFYLNATNEKWKNWRMYDYI VKELPKVLSDNFEQLNTSQASIFGHSMGGHGALTIYLKNTDKYKSVSAFAPIANPINCPWGQKAFSNYLGSTKSDWEEYDATCLIKKNSKVPTTILIDQG EADKFLAEQQLLPHKFEEACKAAGAALTLRMQPGYDHSYYFIATFVDDHIAHHA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 291 Download |
| MAVAPPTAAA LEQLSSSKMF DGFNLRFRHQ SATLGCAMTF SIYLPPSPAS NLPVLYWLSG 60 LTCTDENFII KSGAQRAAAA HGIALVAPDT SPRGLNIEGE SDSYDFGVGA GFYLNATNEK 120 WKNWRMYDYI VKELPKVLSD NFEQLNTSQA SIFGHSMGGH GALTIYLKNT DKYKSVSAFA 180 PIANPINCPW GQKAFSNYLG STKSDWEEYD ATCLIKKNSK VPTTILIDQG EADKFLAEQQ 240 LLPHKFEEAC KAAGAALTLR MQPGYDHSYY FIATFVDDHI AHHAQFLKSA * 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01738 | DLH | 0.009 | 220 | 269 | 50 | + Dienelactone hydrolase family. | ||
| pfam00756 | Esterase | 9.0e-49 | 31 | 282 | 265 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 1.0e-83 | 10 | 290 | 311 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 2.0e-127 | 12 | 287 | 278 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 8 | 289 | 283 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0006508 | proteolysis |
| GO:0008236 | serine-type peptidase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001045351.1 | 0 | 11 | 290 | 14 | 292 | Os01g0939700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001148438.1 | 0 | 1 | 290 | 1 | 290 | esterase D [Zea mays] |
| RefSeq | NP_181684.1 | 0 | 8 | 288 | 2 | 283 | SFGH (S-FORMYLGLUTATHIONE HYDROLASE); S-formylglutathione hydrolase/ hydrolase, acting on ester bonds [Arabidopsis thaliana] |
| RefSeq | XP_002284489.1 | 0 | 13 | 287 | 7 | 282 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002456916.1 | 0 | 8 | 290 | 2 | 284 | hypothetical protein SORBIDRAFT_03g045400 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 10 | 289 | 2 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 10 | 289 | 2 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 10 | 289 | 3 | 280 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 10 | 289 | 3 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 10 | 289 | 3 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Hydropathy |
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