| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G068943_T02 |
| Family | GT20 |
| Protein Properties | Length: 990 Molecular Weight: 110638 Isoelectric Point: 6.6675 |
| Chromosome | Chromosome/Scaffold: 8 Start: 123601206 End: 123609479 |
| Description | trehalose-6-phosphate synthase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT20 | 112 | 516 | 0 |
| MKQRLLVVANRLPVSANRRGEDHWSLEISAGGLVSALLGVKDVDAKWIGWAGVNVPDEVGQRALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLFH YLGLPQEDRLATTRNFESQFDAYKRANQMFADVVYEHYQDGDVIWCHDYHLMFLPKCLKDHDINMKVGWFLHTPFPSSEIYRTLPSRLELLRSVLCADLV GFHTYDYARHFVSACTRILGLEGTPEGVEDQGRLTRVAAFPIGIDSDRFKRALELPAVKRHVSELTERFAGRKVMLGVDRLDMIKGIPQKILAFEKFLEE NPDWNNKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALVTSLRDGMNLVSYEYVACQGSKKGVLI LSEVA | |||
| Full Sequence |
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| Protein Sequence Length: 990 Download |
| MSSDAARGQR GINCTRGDAA AMPTSSPFVG DSGGAGSPIR VERMVRERSR RYDIFASDAM 60 DTDAEAAFAL DGVQSPGRAS PANMEDAGGA AAARPPLAGS RSGFRRLGLR GMKQRLLVVA 120 NRLPVSANRR GEDHWSLEIS AGGLVSALLG VKDVDAKWIG WAGVNVPDEV GQRALTKALA 180 EKRCIPVFLD EEIVHQYYNG YCNNILWPLF HYLGLPQEDR LATTRNFESQ FDAYKRANQM 240 FADVVYEHYQ DGDVIWCHDY HLMFLPKCLK DHDINMKVGW FLHTPFPSSE IYRTLPSRLE 300 LLRSVLCADL VGFHTYDYAR HFVSACTRIL GLEGTPEGVE DQGRLTRVAA FPIGIDSDRF 360 KRALELPAVK RHVSELTERF AGRKVMLGVD RLDMIKGIPQ KILAFEKFLE ENPDWNNKVV 420 LLQIAVPTRT DVPEYQKLTS QVHEIVGRIN GRFGTLTAVP IHHLDRSLDF HALCALYAVT 480 DVALVTSLRD GMNLVSYEYV ACQGSKKGVL ILSEVADRLC MTYNQGVEDV LFIYLFLLSL 540 QFQFAGAAQS LGAGAILVNP WNITEVADSI RHALTMPSDE REKRHRHNYA HVTTHTAQDW 600 AETFVFELND TVAEALLRTR QVPPGLPSQM AIQQYLRSKN RLLILGFNST LTEPVESSGR 660 RGGDQIKEME LKLHPDLKGP LRALCEDERT TVIVLSGSDR SVLDENFGEF KMWLAAEHGM 720 FLRPTYGEWM TTMPEHLNMD WVDSVKHVFE YFTERTPRSH FEHRETSFVW NYKYADVEFG 780 RLQARDMLQH LWTGPISNAA VDVVQGSRSV EVRSVGVTKG AAIDRILGEI VHSENMITPI 840 DYVLCIGHFL GKDEDIYVFF DPEYPSESKV KPEGGSASLD RRPNGRPPSN GRSNSRNPQS 900 RTQKAQQAAS ERSSSSSHSS TSSNHDWREG SSVLDLKGEN YFSCAVGRKR SNARYLLSSS 960 EEVVSFLKEL ATATAGFQAT CADYMHVLG* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 0 | 52 | 978 | 939 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03063 | PLN03063 | 0 | 113 | 973 | 861 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| pfam00982 | Glyco_transf_20 | 0 | 114 | 610 | 503 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| TIGR02400 | trehalose_OtsA | 0 | 115 | 610 | 498 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
| PRK14501 | PRK14501 | 0 | 115 | 847 | 738 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABF70084.1 | 0 | 33 | 973 | 21 | 959 | trehalose-6-phosphate synthase, putative [Musa balbisiana] |
| GenBank | ACI16353.1 | 0 | 112 | 985 | 1 | 854 | trehalose-6-P synthase [Triticum aestivum] |
| GenBank | EAY98715.1 | 0 | 112 | 985 | 1 | 850 | hypothetical protein OsI_20647 [Oryza sativa Indica Group] |
| RefSeq | NP_001123593.2 | 0 | 22 | 989 | 1 | 939 | trehalose-6-phosphate synthase [Zea mays] |
| RefSeq | XP_002440086.1 | 0 | 1 | 985 | 1 | 972 | hypothetical protein SORBIDRAFT_09g025790 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 115 | 612 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 115 | 612 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 115 | 612 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 115 | 612 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 115 | 612 | 3 | 455 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Hydropathy |
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