| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G074514_T01 |
| Family | GT47 |
| Protein Properties | Length: 784 Molecular Weight: 88809.9 Isoelectric Point: 7.1885 |
| Chromosome | Chromosome/Scaffold: 9 Start: 150886125 End: 150890757 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 337 | 691 | 0 |
| KKRPLIYVYDLPAEFDSHLLEGRHYRFQCVNRIYDDMNRTIWTQQLYGAQIALHESILASPHRTLNGDEADYFYVPVLDSCLITRSDDAPHLLLPRDLRR RSYHALEYYRMAHGHIAQQYPYWNRTSGRDHIWFFSWDEGACYAPKEIWKSMMLVHWGNTNTKHKNSTTAYWADNWDDIPLDKRGNHPCFDPRKDLVLPA WKEPNPGAIWLKLWARPRNNRTTLFYFNGNLGSAYEGGRPEDTYSMGIRQKLAAEFGSTPNKQGRLGRQHAADVTVTYLRTEKYYEELASSVFCGVLPGD GWSGRMEDSMLQGCIPVIIQDGIFLPYENVLNYNSFAVRIQEDDIPGLISTLRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 784 Download |
| MFAIRSTKCP VAFVGVAGTL VVLITAVHVF MVPILPASFY YFGSRSSISH PKNVLPAVEV 60 VDSRLKGCFP SDSYGAVAFR GAPWKAEIGR WLAGCHANSS SVDVTEAMGA KRCVKDCSAR 120 GVCNYNLGEC RCFHGYSGKG CEEVLNLECN LPSSPEWPVG QWIVSICAAH CDKTRAMCFC 180 GPGTKYPDRP VAEACGFKTI LPAKPDGPKL TDWKTPDLEN ILTTNSSKLG WCNVVPEDAY 240 SSKVKFKEEC DCKYDGLWGQ FCETRAECSC INQCSGHGHC RGGFCKCDSG YFGIDCSIPS 300 AYSLAYDWPS WLQTPVNLPD LKTLNSTTIG VKAVVQKKRP LIYVYDLPAE FDSHLLEGRH 360 YRFQCVNRIY DDMNRTIWTQ QLYGAQIALH ESILASPHRT LNGDEADYFY VPVLDSCLIT 420 RSDDAPHLLL PRDLRRRSYH ALEYYRMAHG HIAQQYPYWN RTSGRDHIWF FSWDEGACYA 480 PKEIWKSMML VHWGNTNTKH KNSTTAYWAD NWDDIPLDKR GNHPCFDPRK DLVLPAWKEP 540 NPGAIWLKLW ARPRNNRTTL FYFNGNLGSA YEGGRPEDTY SMGIRQKLAA EFGSTPNKQG 600 RLGRQHAADV TVTYLRTEKY YEELASSVFC GVLPGDGWSG RMEDSMLQGC IPVIIQDGIF 660 LPYENVLNYN SFAVRIQEDD IPGLISTLRG INDTQVEFML GNVRQMWQRF FYRDSILLEA 720 QRQKKLFSEE APWSVEVSKL PDDDDVFATF IQVLHYKLYN DPWRQDFLQT KDTRLPNICS 780 RTS* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00054 | EGF_CA | 0.006 | 267 | 296 | 34 | + Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. | ||
| pfam07974 | EGF_2 | 8.0e-5 | 268 | 296 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 3.0e-70 | 336 | 691 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI29877.1 | 0 | 2 | 771 | 31 | 808 | unnamed protein product [Vitis vinifera] |
| GenBank | EAZ25771.1 | 0 | 4 | 783 | 1 | 779 | hypothetical protein OsJ_09611 [Oryza sativa Japonica Group] |
| GenBank | EEC74609.1 | 0 | 4 | 783 | 1 | 737 | hypothetical protein OsI_10218 [Oryza sativa Indica Group] |
| RefSeq | NP_191322.3 | 0 | 1 | 779 | 1 | 788 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002277596.1 | 0 | 2 | 771 | 3 | 780 | PREDICTED: hypothetical protein [Vitis vinifera] |
