y
Basic Information | |
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Species | Zea mays |
Cazyme ID | GRMZM2G076688_T02 |
Family | GT47 |
Protein Properties | Length: 239 Molecular Weight: 26923 Isoelectric Point: 10.3535 |
Chromosome | Chromosome/Scaffold: 3 Start: 178310067 End: 178315309 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 51 | 206 | 2.4e-27 |
ADLRIYVYAEDEIQGLRALLRGRDGTINAATCLKGQWGTQVKVHQFLLKSRFRTFNKDHANLFFVPSYVKCVRMTGALSDKEINQTYVKVLSQMPYFRRS GGRDHIFVFPSGAGAHLFRSWAIFLNRSIILTPEGDRTDKRGTSAFNTWKDIIIPG |
Full Sequence |
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Protein Sequence Length: 239 Download |
MRHHQACSRA HQVGALVLVS ATFLLTRLFD RFLLDTYSSA PINPGRPFSS ADLRIYVYAE 60 DEIQGLRALL RGRDGTINAA TCLKGQWGTQ VKVHQFLLKS RFRTFNKDHA NLFFVPSYVK 120 CVRMTGALSD KEINQTYVKV LSQMPYFRRS GGRDHIFVFP SGAGAHLFRS WAIFLNRSII 180 LTPEGDRTDK RGTSAFNTWK DIIIPGNVDD SMGKAGRLQL VELAKQYPDK LESPELKL* 240 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-18 | 49 | 205 | 157 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EAY93033.1 | 0 | 3 | 238 | 5 | 268 | hypothetical protein OsI_14833 [Oryza sativa Indica Group] |
RefSeq | NP_001131485.1 | 0 | 1 | 238 | 1 | 265 | hypothetical protein LOC100192822 [Zea mays] |
RefSeq | NP_973879.1 | 0 | 7 | 238 | 22 | 301 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002300942.1 | 0 | 7 | 238 | 22 | 299 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002458782.1 | 0 | 1 | 238 | 1 | 265 | hypothetical protein SORBIDRAFT_03g040220 [Sorghum bicolor] |