| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G081841_T01 |
| Family | AA3 |
| Protein Properties | Length: 592 Molecular Weight: 64442.7 Isoelectric Point: 8.531 |
| Chromosome | Chromosome/Scaffold: 7 Start: 98563802 End: 98569524 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 55 | 584 | 0 |
| TTYDYIIVGGGTAGCPLAATLSHRYRVLLLERGGSPYGDRNVSYMQNFHIGLMNMAPDSPSQAFISTDGVINARARVLGGGTCINAGFYSRASPSFIQEA GWDEDLVNKSYPWVEDKIVQWPKIAPWQAALRDGLLQAGVAPFNGYTYDHVSGTKVGGTIFDETGYRHTAADLLAAGDASNLKVLLHASVHKIVFGSRQG RLKARAIGVEFTDEDGRHHQAFLNSNRDSEVIVSAGAIGTPQLLLLSGIGPKNDLKNHNIPVVLHNRYVGKGMADNPMNSIFIPTRSPPRQSLIETVGIT EEGVFIEASSGFGQSSESVHCHHGIMSAEIGQLSTIPPKQRTLEAAQKYAHNKLNLPKEVFHGGFILEKIDGPMSTGHLVLTDTDVRNNPAVTFNYFSHP QDLNRCIYGIKTIERILKTNRFSELSADGAGLSMERVLNMSVQANVNLIPKHTNDTESLEQFCKDTVITIWHYHGGCHVGKVVDQHYRVLGVSGLRVVDG SIFSKSPGTNPQATVMMMGRYMGVKILRER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 592 Download |
| MALSGRALLL FKLLLLLLAC LLFLLELSRG KEEAFSLRNL PPFHKASSYP AGCPTTYDYI 60 IVGGGTAGCP LAATLSHRYR VLLLERGGSP YGDRNVSYMQ NFHIGLMNMA PDSPSQAFIS 120 TDGVINARAR VLGGGTCINA GFYSRASPSF IQEAGWDEDL VNKSYPWVED KIVQWPKIAP 180 WQAALRDGLL QAGVAPFNGY TYDHVSGTKV GGTIFDETGY RHTAADLLAA GDASNLKVLL 240 HASVHKIVFG SRQGRLKARA IGVEFTDEDG RHHQAFLNSN RDSEVIVSAG AIGTPQLLLL 300 SGIGPKNDLK NHNIPVVLHN RYVGKGMADN PMNSIFIPTR SPPRQSLIET VGITEEGVFI 360 EASSGFGQSS ESVHCHHGIM SAEIGQLSTI PPKQRTLEAA QKYAHNKLNL PKEVFHGGFI 420 LEKIDGPMST GHLVLTDTDV RNNPAVTFNY FSHPQDLNRC IYGIKTIERI LKTNRFSELS 480 ADGAGLSMER VLNMSVQANV NLIPKHTNDT ESLEQFCKDT VITIWHYHGG CHVGKVVDQH 540 YRVLGVSGLR VVDGSIFSKS PGTNPQATVM MMGRYMGVKI LRERLGRAAG V* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05199 | GMC_oxred_C | 9.0e-28 | 427 | 573 | 152 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR03970 | Rv0697 | 1.0e-29 | 58 | 573 | 556 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 3.0e-35 | 58 | 573 | 576 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 2.0e-49 | 56 | 589 | 584 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 28 | 591 | 572 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACF81814.1 | 0 | 1 | 591 | 1 | 591 | unknown [Zea mays] |
| GenBank | ACG29139.1 | 0 | 28 | 591 | 27 | 590 | protein HOTHEAD precursor [Zea mays] |
| RefSeq | NP_001062996.1 | 0 | 1 | 591 | 1 | 585 | Os09g0363900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001130910.1 | 0 | 1 | 591 | 1 | 591 | hypothetical protein LOC100192014 [Zea mays] |
| RefSeq | XP_002462276.1 | 0 | 1 | 591 | 1 | 591 | hypothetical protein SORBIDRAFT_02g023010 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 56 | 584 | 26 | 517 | A Chain A, Structure Of Berberine Bridge Enzyme In Complex With Dehydroscoulerine |
| PDB | 3gdp_A | 0 | 56 | 584 | 26 | 517 | A Chain A, Structure Of Berberine Bridge Enzyme In Complex With Dehydroscoulerine |
| PDB | 3gdn_B | 0 | 56 | 584 | 26 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 56 | 584 | 26 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 56 | 584 | 26 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
