y
Basic Information | |
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Species | Zea mays |
Cazyme ID | GRMZM2G089248_T01 |
Family | GT47 |
Protein Properties | Length: 456 Molecular Weight: 50912.1 Isoelectric Point: 8.1386 |
Chromosome | Chromosome/Scaffold: 1 Start: 88995760 End: 88997441 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 29 | 381 | 0 |
CAGRRIHIRGLPPRFNTDLLRHCGANAFPLADPSAAATSVPPCESLANHGLGPRTHPRSRSWYRTDARLLEAFFHRRILERDCLADDPADADAVFLPYYA ALDALPYVIDPALLDESARHGVALAEFLSRDQAHILSRRHGHDHFLVVAGSAWDYAQSPVAEPRLWGSTSLLRLPELANFTFLTLESRTWPWQEHAIPHP TSFHPSSLGHLRAWLARARRSRRATLMLFAGGASRPSRPNIRGSILSECANRTDACVVVDCSGGKCAHEPVRYMRPMLRSKFCLQPPGDTPTRRSTFDAI LAGCVPVFFEDLAARRQYGWHLPPVRYDEFSVHMPKEAVVFGGVRIVETLEAV |
Full Sequence |
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Protein Sequence Length: 456 Download |
MVNPLLIFLP FLSVAALPGN ADAAGPDPCA GRRIHIRGLP PRFNTDLLRH CGANAFPLAD 60 PSAAATSVPP CESLANHGLG PRTHPRSRSW YRTDARLLEA FFHRRILERD CLADDPADAD 120 AVFLPYYAAL DALPYVIDPA LLDESARHGV ALAEFLSRDQ AHILSRRHGH DHFLVVAGSA 180 WDYAQSPVAE PRLWGSTSLL RLPELANFTF LTLESRTWPW QEHAIPHPTS FHPSSLGHLR 240 AWLARARRSR RATLMLFAGG ASRPSRPNIR GSILSECANR TDACVVVDCS GGKCAHEPVR 300 YMRPMLRSKF CLQPPGDTPT RRSTFDAILA GCVPVFFEDL AARRQYGWHL PPVRYDEFSV 360 HMPKEAVVFG GVRIVETLEA VPEEEVRRMR QRVLEVAPRV VYRRHGSTPE LREAVKDAVD 420 LAVDGVLQRI RWRTRALEDG PPERIYAQEE DSVDR* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-42 | 28 | 381 | 366 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG13471.2 | 0 | 27 | 454 | 30 | 462 | AC026758_8 hypothetical protein [Oryza sativa Japonica Group] |
GenBank | ACN36955.1 | 0 | 1 | 455 | 1 | 455 | unknown [Zea mays] |
RefSeq | NP_001065337.1 | 0 | 27 | 454 | 169 | 601 | Os10g0553600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002466037.1 | 0 | 29 | 454 | 45 | 481 | hypothetical protein SORBIDRAFT_01g050380 [Sorghum bicolor] |
RefSeq | XP_002467522.1 | 0 | 1 | 454 | 1 | 449 | hypothetical protein SORBIDRAFT_01g029520 [Sorghum bicolor] |