| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G129620_T01 |
| Family | GT2 |
| Protein Properties | Length: 398 Molecular Weight: 43961.5 Isoelectric Point: 10.4153 |
| Chromosome | Chromosome/Scaffold: 1 Start: 293575617 End: 293578168 |
| Description | Nucleotide-diphospho-sugar transferases superfamily protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT2 | 132 | 327 | 7.2e-34 |
| SLIVPAYNEEYRLPEALTETLNYLKRRSTADKSFSYEVLIVDDGSTDGTSKVAFSFVKKHKIDNVRVLLLGRNHGKGEAVRKGMLHSRGELLLMLDADGA TKVTDLEKLEAQVHALAKKAKSSPGTSTSSSQNLSDVEVAVFGSRAHLEKQALATRKWYRNFLMKGFHLVVLLTAGPGIKDTQCGFKMFTRAAARK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 398 Download |
| MPNVQPGRPG RLPVCLRRAD LPNSRTRKPT RRPEQRVDSA PAVGTATMAA AWPLSAIAGI 60 LPASLSLTLL LATLVSILVL GAAAFFFEHI RKIGCMHSLE RSAVSDAFFE DPNSLKKVPC 120 PSVLDPPEKY ISLIVPAYNE EYRLPEALTE TLNYLKRRST ADKSFSYEVL IVDDGSTDGT 180 SKVAFSFVKK HKIDNVRVLL LGRNHGKGEA VRKGMLHSRG ELLLMLDADG ATKVTDLEKL 240 EAQVHALAKK AKSSPGTSTS SSQNLSDVEV AVFGSRAHLE KQALATRKWY RNFLMKGFHL 300 VVLLTAGPGI KDTQCGFKMF TRAAARKLFT NIRLKRWCFD VELVYLCKRL RIPMVEVSVN 360 WTEIPGSKVR MTSIMHMVFE LLLIKVGYGL GIWKIGS* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06442 | DPM1_like | 1.0e-20 | 133 | 357 | 226 | + DPM1_like represents putative enzymes similar to eukaryotic DPM1. Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily. | ||
| pfam00535 | Glycos_transf_2 | 2.0e-23 | 132 | 329 | 198 | + Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. | ||
| cd04179 | DPM_DPG-synthase_like | 3.0e-50 | 133 | 347 | 215 | + DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily. | ||
| PTZ00260 | PTZ00260 | 8.0e-100 | 130 | 395 | 270 | + dolichyl-phosphate beta-glucosyltransferase; Provisional | ||
| cd04188 | DPG_synthase | 2.0e-103 | 133 | 368 | 236 | + DPG_synthase is involved in protein N-linked glycosylation. UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAO18453.1 | 0 | 88 | 397 | 71 | 380 | putative dolichyl-phosphate beta-glucosyltransferase [Oryza sativa Japonica Group] |
| GenBank | EEC76428.1 | 0 | 49 | 397 | 3 | 352 | hypothetical protein OsI_14108 [Oryza sativa Indica Group] |
| RefSeq | NP_001051729.1 | 0 | 49 | 397 | 3 | 352 | Os03g0821800 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001140935.1 | 0 | 88 | 397 | 41 | 350 | hypothetical protein LOC100273013 [Zea mays] |
| RefSeq | XP_002283615.1 | 0 | 97 | 397 | 35 | 336 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3o3p_B | 0.0003 | 168 | 229 | 128 | 189 | A Chain A, Crystal Structure Of Human Glycogenin-1 (Gyg1), Apo Form |
| PDB | 3o3p_A | 0.0003 | 168 | 229 | 128 | 189 | A Chain A, Crystal Structure Of Human Glycogenin-1 (Gyg1), Apo Form |
| PDB | 3kia_C | 0.0003 | 168 | 229 | 128 | 189 | A Chain A, Crystal Structure Of Human Glycogenin-1 (Gyg1), Apo Form |
| PDB | 3kia_A | 0.0003 | 168 | 229 | 128 | 189 | A Chain A, Crystal Structure Of Human Glycogenin-1 (Gyg1), Apo Form |
| PDB | 3f1y_C | 0.0003 | 168 | 229 | 128 | 189 | A Chain A, Mannosyl-3-Phosphoglycerate Synthase From Rubrobacter Xylanophilus |
