| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G134308_T01 |
| Family | GT47 |
| Protein Properties | Length: 413 Molecular Weight: 46710.9 Isoelectric Point: 7.3797 |
| Chromosome | Chromosome/Scaffold: 8 Start: 160385132 End: 160388604 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 45 | 340 | 0 |
| KLKVFVYEMPRKYNKMLVDKDSRCLQHMFAAEIFMHQFLLSSAVRTLDPEAADWFYTPVYTTCDLTPQGFPLPFRAPRMMRSAIRYVAATWPFWNRTDGA DHFFLTPHDFGACFHYQEERAVERGILPLLRRATLVQTFGQRNHVCLQDGSITVPPYASPHRLQAHLVGPGTPRSIFVYFRGLFYDMGNDPEGGYYARGA RASVWENFKDNPLFDISTEHPATYYEDMQRAIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEDMSVFVAERDVPRLDSILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 413 Download |
| MRPLVAAVLL VTICVVAAAP LQRHHKPGRT SGNAVGVLDD DPVGKLKVFV YEMPRKYNKM 60 LVDKDSRCLQ HMFAAEIFMH QFLLSSAVRT LDPEAADWFY TPVYTTCDLT PQGFPLPFRA 120 PRMMRSAIRY VAATWPFWNR TDGADHFFLT PHDFGACFHY QEERAVERGI LPLLRRATLV 180 QTFGQRNHVC LQDGSITVPP YASPHRLQAH LVGPGTPRSI FVYFRGLFYD MGNDPEGGYY 240 ARGARASVWE NFKDNPLFDI STEHPATYYE DMQRAIFCLC PLGWAPWSPR LVEAVVFGCI 300 PVIIADDIVL PFADAIPWED MSVFVAERDV PRLDSILTSI PLPDILRRQR LLARDSVKRA 360 LLFHQPARPG DAFHQVLNGL ARKLPHREGV FLQPGEKALD WDAGLESDLK PW* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-80 | 45 | 340 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG43504.1 | 0 | 24 | 412 | 32 | 420 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
| GenBank | ACN31576.1 | 0 | 1 | 412 | 1 | 412 | unknown [Zea mays] |
| GenBank | ACR34554.1 | 0 | 1 | 412 | 1 | 412 | unknown [Zea mays] |
| RefSeq | NP_001045262.1 | 0 | 25 | 412 | 35 | 422 | Os01g0926400 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002459015.1 | 0 | 5 | 412 | 8 | 415 | hypothetical protein SORBIDRAFT_03g044510 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
