| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G149189_T01 |
| Family | GT47 |
| Protein Properties | Length: 473 Molecular Weight: 52728.7 Isoelectric Point: 10.2419 |
| Chromosome | Chromosome/Scaffold: 5 Start: 184064747 End: 184066999 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 139 | 423 | 0 |
| ERKFKIWTYREGEPPLAHLGPSADIYSIEGQFLEEIEDPRNPFAARDPGEAHAFLLPVSVCNLVHYIYRLNTTAYMAHMRRALADYVDVVAHKYPYWNRS RGADHVIVSCHDWAPLVSEANRELYANAIRVLCNANTSEGFRPRKDATLPEVNLADGLLRRPTLGLPPENRTTLAFFAGGMHGHIRRALLGYWLGRKDPD MDIHEYLPAGQDYHALMARARFCLCPSGFEVASPRVVESVFTGCVPVIISDGYPPPFSDVLDWSKMSVTVPPARIPELKAVLKGV | |||
| Full Sequence |
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| Protein Sequence Length: 473 Download |
| MENGGRVAAI AVPLLVSALF VAAFLLPPYS SSLGGGGGGA ESASIREHFL RHVPQKPSRT 60 PPVPSAQLAG KVSVGPIEES LARSRAAIRR AARGAPAATA AAENARRRRS FKDVGDAFVP 120 RGAIYRNPRA FHRSYLEMER KFKIWTYREG EPPLAHLGPS ADIYSIEGQF LEEIEDPRNP 180 FAARDPGEAH AFLLPVSVCN LVHYIYRLNT TAYMAHMRRA LADYVDVVAH KYPYWNRSRG 240 ADHVIVSCHD WAPLVSEANR ELYANAIRVL CNANTSEGFR PRKDATLPEV NLADGLLRRP 300 TLGLPPENRT TLAFFAGGMH GHIRRALLGY WLGRKDPDMD IHEYLPAGQD YHALMARARF 360 CLCPSGFEVA SPRVVESVFT GCVPVIISDG YPPPFSDVLD WSKMSVTVPP ARIPELKAVL 420 KGVSERRYRV LRARVLQAQR HFVVHRPARR FDMIRMVLHS IWLRRINVRL PY* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-68 | 138 | 423 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD19700.1 | 0 | 138 | 472 | 1 | 345 | exostosin-like protein [Oryza sativa Japonica Group] |
| GenBank | EAY86665.1 | 0 | 37 | 472 | 33 | 482 | hypothetical protein OsI_08049 [Oryza sativa Indica Group] |
| RefSeq | NP_197526.4 | 0 | 77 | 471 | 27 | 408 | catalytic [Arabidopsis thaliana] |
| Swiss-Prot | Q3E9A4 | 0 | 77 | 471 | 85 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
| RefSeq | XP_002454169.1 | 0 | 138 | 472 | 1 | 338 | hypothetical protein SORBIDRAFT_04g025885 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
