| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G315692_T01 |
| Family | GT47 |
| Protein Properties | Length: 359 Molecular Weight: 40409 Isoelectric Point: 8.8664 |
| Chromosome | Chromosome/Scaffold: 2 Start: 228537718 End: 228538817 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 2 | 275 | 0 |
| KQYECLTNRSAAAAAVFVPFYAGFDFVRYHWGYDNAARDAASVDLARWLMARPEWRRMGGRDHFLVAGRTGWDFRRSNNVDPDWGNDLLVMPAGRNMSVL VLESAMLHGGDYPVPYPTYFHPRSDADVARWQDRVRGQRRTWLMAFVGAPRPDVPINIRVRDHVIAQCTASSACTMLGCARATGSTQCHTPGNIMRLFKK TTFCLQPPGDTCTRRSAFDSMVAGCIPVFFHPGSAYKQYRWHLPRDDHLRYSVYIPDADVRERNVSIEAVLRAI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 359 Download |
| MKQYECLTNR SAAAAAVFVP FYAGFDFVRY HWGYDNAARD AASVDLARWL MARPEWRRMG 60 GRDHFLVAGR TGWDFRRSNN VDPDWGNDLL VMPAGRNMSV LVLESAMLHG GDYPVPYPTY 120 FHPRSDADVA RWQDRVRGQR RTWLMAFVGA PRPDVPINIR VRDHVIAQCT ASSACTMLGC 180 ARATGSTQCH TPGNIMRLFK KTTFCLQPPG DTCTRRSAFD SMVAGCIPVF FHPGSAYKQY 240 RWHLPRDDHL RYSVYIPDAD VRERNVSIEA VLRAIPPAAV QRMREEVVRL IPRVLYADPR 300 SKLETVKDAV DVAVEGVLDT VARIRNGEYV DSGGPVTEDP PNLFASTESR FRPAQADR* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-51 | 1 | 275 | 285 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001048943.1 | 0 | 1 | 327 | 160 | 481 | Os03g0144300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002465869.1 | 0 | 1 | 351 | 165 | 515 | hypothetical protein SORBIDRAFT_01g047310 [Sorghum bicolor] |
| RefSeq | XP_002468519.1 | 0 | 1 | 356 | 126 | 481 | hypothetical protein SORBIDRAFT_01g047290 [Sorghum bicolor] |
| RefSeq | XP_002468520.1 | 0 | 1 | 353 | 133 | 472 | hypothetical protein SORBIDRAFT_01g047300 [Sorghum bicolor] |
| RefSeq | XP_002468521.1 | 0 | 1 | 353 | 137 | 499 | hypothetical protein SORBIDRAFT_01g047315 [Sorghum bicolor] |
| Hydropathy |
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