| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G448834_T04 |
| Family | GT47 |
| Protein Properties | Length: 388 Molecular Weight: 44282.8 Isoelectric Point: 6.3186 |
| Chromosome | Chromosome/Scaffold: 3 Start: 157086600 End: 157088110 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 20 | 315 | 0 |
| KLKVFVYEMPRKYNRMLLDKDSRCLHHMFAAEIFMHQFLLSSAVRTLDPEEADWFYTPAYTTCDLTPQGFPLPFRAPRIMRSAIRYVATTWPFWNRTDGA DHFFLTPHDFGACFHYQEERAMERGILPLLRRATLVQTFGQRNHVCLQDGSITVPPYADPGKMQAHLISPGTPRSIFVYFRGLFYDMGNDPEGGYYARGA RASVWENFKDNPLFDISTEHPSTYYEDMQRAIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEDISVFVAERDVPRLDSILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 388 Download |
| MQRSHLWDAV GVLDDDPVGK LKVFVYEMPR KYNRMLLDKD SRCLHHMFAA EIFMHQFLLS 60 SAVRTLDPEE ADWFYTPAYT TCDLTPQGFP LPFRAPRIMR SAIRYVATTW PFWNRTDGAD 120 HFFLTPHDFG ACFHYQEERA MERGILPLLR RATLVQTFGQ RNHVCLQDGS ITVPPYADPG 180 KMQAHLISPG TPRSIFVYFR GLFYDMGNDP EGGYYARGAR ASVWENFKDN PLFDISTEHP 240 STYYEDMQRA IFCLCPLGWA PWSPRLVEAV VFGCIPVIIA DDIVLPFADA IPWEDISVFV 300 AERDVPRLDS ILTSIPLPDI LRRQRLLARD SVKQALLFHQ PARPGDAFHQ VLNGLARKLP 360 HGEGVFLQPG EKALDWDAGL QSDLKPW* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-80 | 20 | 315 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG43504.1 | 0 | 8 | 387 | 41 | 420 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
| GenBank | ACN31576.1 | 0 | 8 | 387 | 33 | 412 | unknown [Zea mays] |
| GenBank | ACR34554.1 | 0 | 8 | 387 | 33 | 412 | unknown [Zea mays] |
| RefSeq | NP_001045262.1 | 0 | 12 | 387 | 47 | 422 | Os01g0926400 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002459015.1 | 0 | 8 | 387 | 36 | 415 | hypothetical protein SORBIDRAFT_03g044510 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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