| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G480451_T01 |
| Family | GH79 |
| Protein Properties | Length: 925 Molecular Weight: 104088 Isoelectric Point: 7.3705 |
| Chromosome | Chromosome/Scaffold: 1 Start: 158479095 End: 158501168 |
| Description | glucuronidase 2 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH79 | 753 | 917 | 3.1e-35 |
| FNPGQCLLSALLWHRLMGTGVLSLDISGSPYLRPYAHCAKQKGGIALVLLNLHRTMGFMVSVRNDINVNLAEGQGIRRDNAFVHGLKRTVSWVGSKASDG FSKREEYHLSAQDGNPFARTMLLNGVPLELTEDGDIPPLYPVEVSANSPIYVAPLTIAFVVFPDF | |||
| GH79 | 515 | 754 | 0 |
| EFVCATIDWWPPEKCNYDQCPWGRASVLNLDLTNPLLAKAIQAFSPLRIRVGGSLQDQVLYGTPNLGLPCDPFTKVSSGLFEFSQGCITLERWDDINDLF LNTGAVVTFGLNALQGRHQIRKGVWGGPWNSSNAREFIEYTASKNYPIDSWEFGNELSGSGVGASVAAEQYGKDLVVLQTIVNELYGDSSKPLVVAPGGF YDQKWFAQLLEASGPNVLNAVTHHIYNLGAGGDTTVLNFN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 925 Download |
| MHLSKSARRQ TTMHLGRRTS WQAKVHRCVM MMTMGRTTME RPMTRLLQRH RQQTSVGSRS 60 RTSTARESEL DEQLRQQQQQ VQQLSQQVQM MQMYSAQMVS QMGPQFTRPS QSGQTPNTNE 120 THGSETGQGN PQMDMRWSMP PRGQILPPPQ LGMGYWSPPP WGYPTHPMGP WGRPHGQHSH 180 FHHQRSMSPG YFTNLLNRDN DDVFILDENM GNENEVMESE SPPMNDMISQ SKPKGRSKNF 240 NEAEDILLIS SYLNISKDAV VGRDQKDGRF WERVEKYFHD NKTFESERNW SSLKHRWSTI 300 HKEVSLFQGF VDAVERKNES GKTMSDKLAQ ANTMFQELKG KAFSLFHAWN ILKDEPKWAE 360 EKISKEYNAN GEDHPNSERP LGRKAEKEKA KGKKRSEEEH DPFIDEVKKM RESLRANERN 420 VMKGSTINYY PRSTTACRCV PEMKVAILAD AEWWLLPGGD QREYTRWNIG SGSMRLWCIF 480 LLPLLCQLAG VRSEDYSDVT VIVRGSETIA STSGEFVCAT IDWWPPEKCN YDQCPWGRAS 540 VLNLDLTNPL LAKAIQAFSP LRIRVGGSLQ DQVLYGTPNL GLPCDPFTKV SSGLFEFSQG 600 CITLERWDDI NDLFLNTGAV VTFGLNALQG RHQIRKGVWG GPWNSSNARE FIEYTASKNY 660 PIDSWEFGNE LSGSGVGASV AAEQYGKDLV VLQTIVNELY GDSSKPLVVA PGGFYDQKWF 720 AQLLEASGPN VLNAVTHHIY NLGAGGDTTV LNFNPGQCLL SALLWHRLMG TGVLSLDISG 780 SPYLRPYAHC AKQKGGIALV LLNLHRTMGF MVSVRNDINV NLAEGQGIRR DNAFVHGLKR 840 TVSWVGSKAS DGFSKREEYH LSAQDGNPFA RTMLLNGVPL ELTEDGDIPP LYPVEVSANS 900 PIYVAPLTIA FVVFPDFEAE ACGR* 960 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam14303 | NAM-associated | 9.0e-5 | 341 | 380 | 40 | + No apical meristem-associated C-terminal domain. This domain is found in a number of different types of plant proteins including NAM-like proteins. | ||
| pfam03662 | Glyco_hydro_79n | 2.0e-145 | 498 | 752 | 256 | + Glycosyl hydrolase family 79, N-terminal domain. Family of endo-beta-N-glucuronidase, or heparanase. Heparan sulfate proteoglycans (HSPGs) play a key role in the self- assembly, insolubility and barrier properties of basement membranes and extracellular matrices. Hence, cleavage of heparan sulfate (HS) affects the integrity and functional state of tissues and thereby fundamental normal and pathological phenomena involving cell migration and response to changes in the extracellular micro-environment. Heparanase degrades HS at specific intra-chain sites. The enzyme is synthesised as a latent approximately 65 kDa protein that is processed at the N-terminus into a highly active approximately 50 kDa form. Experimental evidence suggests that heparanase may facilitate both tumour cell invasion and neovascularization, both critical steps in cancer progression. The enzyme is also involved in cell migration associated with inflammation and autoimmunity. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| GO:0016798 | hydrolase activity, acting on glycosyl bonds |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACR34666.1 | 0 | 470 | 755 | 32 | 319 | unknown [Zea mays] |
| GenBank | ACR34666.1 | 0 | 745 | 924 | 393 | 575 | unknown [Zea mays] |
| RefSeq | NP_001130921.1 | 0 | 470 | 755 | 23 | 310 | hypothetical protein LOC100192026 [Zea mays] |
| RefSeq | XP_002442385.1 | 0 | 489 | 755 | 16 | 284 | hypothetical protein SORBIDRAFT_08g019250 [Sorghum bicolor] |
| RefSeq | XP_002442385.1 | 0 | 745 | 924 | 358 | 540 | hypothetical protein SORBIDRAFT_08g019250 [Sorghum bicolor] |
| Hydropathy |
|---|
 |