| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM5G837822_T01 |
| Family | GH18 |
| Protein Properties | Length: 312 Molecular Weight: 32398.7 Isoelectric Point: 9.0777 |
| Chromosome | Chromosome/Scaffold: 3 Start: 176570295 End: 176571270 |
| Description | chitinase A |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 35 | 259 | 3e-26 |
| IAIYWGQNGNEGTLAQTCATGNYRFVNVAFLPTFGRGQTPALNLAGHCDPASGGCTGVGADVKACQRMGVKVLLSIGGGVGSYGLSSRADARSVAAYLWD NYLGGGGSESRPLGDAVLDGVDFDIESGGGMYWDDLARFLKSYSRRGRGRARRPVYLSAAPQCPFPDASLGTALATGLFDYVWVQFYNNPPCQYSASAGV GSLAQAWAQWTSIRAGRVFLGLPAA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 312 Download |
| MGRRSSQFPS MALAMATVLM ALGGVAATAR AGGGIAIYWG QNGNEGTLAQ TCATGNYRFV 60 NVAFLPTFGR GQTPALNLAG HCDPASGGCT GVGADVKACQ RMGVKVLLSI GGGVGSYGLS 120 SRADARSVAA YLWDNYLGGG GSESRPLGDA VLDGVDFDIE SGGGMYWDDL ARFLKSYSRR 180 GRGRARRPVY LSAAPQCPFP DASLGTALAT GLFDYVWVQF YNNPPCQYSA SAGVGSLAQA 240 WAQWTSIRAG RVFLGLPAAP QAAGSGFVPA SDLVAQVLPV VKNSTKYGGI MLWSRYYDGL 300 TGYSDAVKSY V* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00598 | GH18_chitinase-like | 2.0e-5 | 98 | 222 | 134 | + The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have been identified in viruses, bacteria, fungi, protozoan parasites, insects, and plants. The structure of the GH18 domain is an eight-stranded beta/alpha barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. The GH18 family includes chitotriosidase, chitobiase, hevamine, zymocin-alpha, narbonin, SI-CLP (stabilin-1 interacting chitinase-like protein), IDGF (imaginal disc growth factor), CFLE (cortical fragment-lytic enzyme) spore hydrolase, the type III and type V plant chitinases, the endo-beta-N-acetylglucosaminidases, and the chitolectins. The GH85 (glycosyl hydrolase, family 85) ENGases (endo-beta-N-acetylglucosaminidases) are closely related to the GH18 chitinases and are included in this alignment model. | ||
| COG3469 | COG3469 | 7.0e-9 | 56 | 298 | 271 | + Chitinase [Carbohydrate transport and metabolism] | ||
| cd02871 | GH18_chitinase_D-like | 6.0e-12 | 57 | 310 | 305 | + GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus. | ||
| pfam00704 | Glyco_hydro_18 | 3.0e-27 | 37 | 298 | 339 | + Glycosyl hydrolases family 18. | ||
| cd02877 | GH18_hevamine_XipI_class_III | 7.0e-127 | 37 | 309 | 280 | + This conserved domain family includes xylanase inhibitor Xip-I, and the class III plant chitinases such as hevamine, concanavalin B, and PPL2, all of which have a glycosyl hydrolase family 18 (GH18) domain. Hevamine is a class III endochitinase that hydrolyzes the linear polysaccharide chains of chitin and peptidoglycan and is important for defense against pathogenic bacteria and fungi. PPL2 (Parkia platycephala lectin 2) is a class III chitinase from Parkia platycephala seeds that hydrolyzes beta(1-4) glycosidic bonds linking 2-acetoamido-2-deoxy-beta-D-glucopyranose units in chitin. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAA22266.1 | 0 | 33 | 311 | 30 | 305 | basic class III chitinase OsChib3b [Oryza sativa Japonica Group] |
| GenBank | EAZ14223.1 | 0 | 35 | 311 | 23 | 296 | hypothetical protein OsJ_04148 [Oryza sativa Japonica Group] |
| RefSeq | NP_001044872.1 | 0 | 33 | 311 | 30 | 305 | Os01g0860500 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001150942.1 | 0 | 1 | 311 | 1 | 314 | hevamine-A [Zea mays] |
| RefSeq | XP_002456672.1 | 0 | 4 | 311 | 3 | 303 | hypothetical protein SORBIDRAFT_03g040600 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2hvm_A | 0 | 33 | 307 | 1 | 269 | A Chain A, Crystal Structure Of Pichia Pastoris Phosphofructokinase In The T- State |
| PDB | 1llo_A | 0 | 33 | 307 | 1 | 269 | A Chain A, Crystal Structure Of Pichia Pastoris Phosphofructokinase In The T- State |
| PDB | 1hvq_A | 0 | 33 | 307 | 1 | 269 | A Chain A, Crystal Structures Of Hevamine, A Plant Defence Protein With Chitinase And Lysozyme Activity, And Its Complex With An Inhibitor |
| PDB | 1kr0_A | 0 | 33 | 307 | 1 | 269 | A Chain A, Hevamine Mutant D125aY183F IN COMPLEX WITH TETRA-Nag |
| PDB | 1kr1_A | 0 | 33 | 307 | 1 | 269 | A Chain A, Hevamine Mutant D125aE127A IN COMPLEX WITH TETRA-Nag |
