| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01001097001 |
| Family | GT47 |
| Protein Properties | Length: 391 Molecular Weight: 44476 Isoelectric Point: 6.3191 |
| Chromosome | Chromosome/Scaffold: 1 Start: 22621561 End: 22626108 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 45 | 282 | 0 |
| RLKVFVYELPSKYNKKILQKDPRCLNHMFAAEIFMHRFLLSSPVRTLNPEEADWFYTPIYTTCDLTPNGLPLPFKSPRMMRSAIQLISSNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIERGILPLLQRATLVQTFGQRNHVCLNEGSITIPPYAPPQKMQAHLIPQETPRSIFVYFRGLFYDVNNDPEGGYYARGA RAAVWENFKDNPLFDISTEHPTTYYEDMQRAIFCLCPL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 391 Download |
| MGVWIWVLVF GFVWGIGAHG LDRHPHTERI SGSAGDVLED DPVGRLKVFV YELPSKYNKK 60 ILQKDPRCLN HMFAAEIFMH RFLLSSPVRT LNPEEADWFY TPIYTTCDLT PNGLPLPFKS 120 PRMMRSAIQL ISSNWPYWNR TEGADHFFVV PHDFGACFHY QEEKAIERGI LPLLQRATLV 180 QTFGQRNHVC LNEGSITIPP YAPPQKMQAH LIPQETPRSI FVYFRGLFYD VNNDPEGGYY 240 ARGARAAVWE NFKDNPLFDI STEHPTTYYE DMQRAIFCLC PLADDIVLPF ADAIPWEEIG 300 VFVAEEDVPN LDTILTSIPP EVILRKQRLL ANPSMKQAML FPQPAQSGDA FHQILNGLAR 360 KLPHNKNVYL KPGENALNWT AGPVGDLKPW * 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-62 | 45 | 318 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI29266.1 | 0 | 22 | 390 | 22 | 390 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002284685.1 | 0 | 3 | 390 | 7 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002297880.1 | 0 | 3 | 390 | 5 | 412 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002318180.1 | 0 | 1 | 390 | 1 | 417 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 1 | 390 | 1 | 417 | catalytic, putative [Ricinus communis] |
